Evidence map›Paper›PMID 34557690›Full record

ArticleJACC. Case reports2021

Rare TBX4 Variant Causing Pulmonary Arterial Hypertension With Small Patella Syndrome in an Adult Man.

Sanskriti Shrivastava, Teresa M Kruisselbrink, Akanksha Mohananey, Brittany C Thomas, Sudhir S Kushwaha, Naveen L Pereira

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular Function and Contribution ofAmerican journal of respiratory and critical care medicine · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sanskriti ShrivastavaDepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Teresa M KruisselbrinkDepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Akanksha MohananeyDepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Brittany C ThomasDepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Sudhir S KushwahaDepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Naveen L PereiraDepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small patella syndrome presents with small or absent patellae and may result in pulmonary arterial hypertension, typically in children. A pathogenic canonical splice site variant, c.1021+1G>A in the T-box transcription factor 4 (

Indexed as

next-generation sequencingPAH, pulmonary arterial hypertensionpulmonary artery hypertensionRV, right ventriclesmall patella syndromeSPS, small patella syndromeTBX-4TBX-4, T-box transcription factor-4

Identifiers

PMID34557690
PMCPMC8446047
OpenAlexW3199290361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.