Evidence map›Paper›PMID 34557587›Full record

ArticleTransplantation direct2021

Liver Transplantation With Grafts From Super Obese Donors.

Paola A Vargas, J Michael Cullen, Curtis Argo, Zachary Henry, Matthew J Stotts, Nicolas Intagliata, Patrick Northup, Jose Oberholzer, Shawn Pelletier, Nicolas Goldaracena

Abstract read
In one paragraph

Article in Transplantation direct, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paola A VargasDepartment of Surgery, Division of Transplant Surgery, University of Virginia Health System, Charlottesville, VA.
J Michael CullenDepartment of Surgery, University of Virginia Health System, Charlottesville, VA.
Curtis ArgoDivision of Gastroenterology, Department of Medicine, University of Virginia Health System, Charlottesville, VA.
Zachary HenryDivision of Gastroenterology, Department of Medicine, University of Virginia Health System, Charlottesville, VA.
Matthew J StottsDivision of Gastroenterology, Department of Medicine, University of Virginia Health System, Charlottesville, VA.
Nicolas IntagliataDivision of Gastroenterology, Department of Medicine, University of Virginia Health System, Charlottesville, VA.
Patrick NorthupDivision of Gastroenterology, Department of Medicine, University of Virginia Health System, Charlottesville, VA.
Jose OberholzerDepartment of Surgery, Division of Transplant Surgery, University of Virginia Health System, Charlottesville, VA.
Shawn PelletierDepartment of Surgery, Division of Transplant Surgery, University of Virginia Health System, Charlottesville, VA.
Nicolas GoldaracenaDepartment of Surgery, Division of Transplant Surgery, University of Virginia Health System, Charlottesville, VA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are limited data on liver transplant (LT) outcomes with grafts from super obese donors. The present study aims to evaluate a unique cohort of recipients following LT using grafts from donors with body mass index (BMI) ≥50.

methodsPatients receiving grafts from donors with BMI ≥50 and BMI <50 from 2010 to 2019 were identified. A 1:2 case-control match was conducted to compare outcomes between the groups. Survival was analyzed using the Kaplan-Meier curves.

resultsSix hundred sixty-five adult LTs were performed in the study period. Eighteen patients receiving a graft from a donor with BMI ≥50 were identified and matched to 36 patients receiving a graft from a donor with BMI <50. Grafts from male donors were significantly lower in the donor BMI ≥50 group when compared with the donor BMI <50 group (16.7% versus 66.7%,

conclusionsLT with carefully selected grafts from super obese donors can be safely performed with outcomes comparable with non-super obese donor livers. Therefore, these types of grafts could represent a safe means to expand the donor pool.

Identifiers

PMID34557587
PMCPMC8454911

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