Evidence map›Paper›PMID 34557583›Full record

ArticleTransplantation direct2021

Comanagement With Nephrologist Care Is Associated With Fewer Cardiovascular Events Among Liver Transplant Recipients With Chronic Kidney Disease.

Patrick T Campbell, Megan Kosirog, Blessing Aghaulor, Dyanna Gregory, Stewart Pine, Amna Daud, Arighno Das, Daniel J Finn, Josh Levitsky, Jane L Holl and 2 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Patrick T CampbellDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Megan KosirogDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Blessing AghaulorDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Dyanna GregoryDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Stewart PineDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Amna DaudComprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.
Arighno DasDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Daniel J FinnDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Josh LevitskyDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Jane L HollCenter for Healthcare Delivery Science and Innovation, University of Chicago Medicine, Chicago, IL.
Donald M Lloyd-JonesDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
Lisa B VanWagnerDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL.
Northwestern University · USUniversity of Chicago · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Implementation science to improve cardiovascular outcomes among liver transplant recipientsK23HL136891 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI VANWAGNER, LISA B · 2017 to 2020
$757k
NCATS NIH HHS UL1 TR001422NHLBI NIH HHS K23 HL136891
6 · The paper itself

Abstract

Chronic kidney disease (CKD) is associated with cardiovascular (CV) events, a leading complication in liver transplant recipients (LTRs). Timely subspecialty care is associated with improved clinical outcomes in patients with CKD. This study sought to assess associations between nephrology comanagement and CV events among LTRs at risk for or with CKD.

methodsLTRs with CKD plus those at risk were identified in an inception cohort at a single tertiary care network between 2010 and 2016, using electronic health record data and manual chart review. CKD was defined as estimated glomerular filtration rate <60 mL/min/1.73 m

resultsAmong 602 LTRs followed for up to 6 y posttransplant, prevalence of CKD plus those at risk increased yearly (71% in year 1, 86% in year 6) (

conclusionsAmong LTRs with CKD, nephrology comanagement may be associated with lower CV events. A prospective study is needed to identify the reasons for improved outcomes and barriers to nephrology referral.

Identifiers

PMID34557583
PMCPMC8454906
OpenAlexW3200169528

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.