Evidence map›Paper›PMID 34557386›Full record

ReviewSchizophrenia research. Cognition2022

Single episode brief psychotic disorder versus bipolar disorder: A diffusion tensor imaging and executive functions study.

Zeinab El Nagar, Heba H El Shahawi, Safeya M Effat, Mona M El Sheikh, Ahmed Adel, Yosra A Ibrahim, Ola M Aufa

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Schizophrenia research. Cognition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zeinab El NagarInstitute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Heba H El ShahawiInstitute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Safeya M EffatInstitute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Mona M El SheikhInstitute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Ahmed AdelInstitute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Yosra A IbrahimRadiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Ola M AufaInstitute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite fast progress in neuroscientific approaches, the neurobiological continuum links psychotic spectrum, and affective disorder is obscure. White matter WM abnormalities found utilizing Diffusion Tensor Imaging (DTI) showing impaired communication in both disorders have been consistently demonstrated; however, direct comparisons of findings between them are scarce. This study aims to study WM abnormalities in single episode bipolar I disorder, and single episode brief psychotic disorder related to healthy control with the association of executive function.

methodsA cross-sectional case-control study was used to assess 60 subjects divided into 20 patients with single episode bipolar I disorder, 20 individuals with single episode brief psychotic disorder (both groups of patients were in remission), and 20 healthy controls. The present study examined the superior longitudinal fasciculus (SLF), and cingulum bundle fractional anisotropy (FA) determined from DTI images symmetrically and connected these results with cognitive functions as assessed by the trail making test (TMT) and Wisconsin card sorting test (WCST).

resultsDTI data indicated that the psychotic group had a significant decrease in FA of the right SLF (p-value less than 0.001), left SLF (p-value less than 0.001), and left cingulum (p-value less than 0.001) than the bipolar I group. In terms of executive functioning, the psychotic group performed significantly worse than the bipolar I group on the TMT part B (p-value less than 0.001), the WCST (number of classifications fulfilled) (p-value less than 0.001), and perseverative errors (p-value less than 0.001).

conclusionEven after clinical remission, individuals with single episode brief psychotic disorder had more pronounced white matter impairments and executive function deficiencies than individuals with single episode bipolar I disorder.

Indexed as

Bipolar disorderBrief psychotic disorderDiffusion tensor imagingExecutive functionsSingle episode

Identifiers

PMID34557386
PMCPMC8446778
OpenAlexW3201140383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.