Evidence map›Paper›PMID 34557270›Full record

ReviewIranian journal of microbiology2021

Astaxanthin protective barrier and its ability to improve the health in patients with COVID-19.

Ali-Reza Ahmadi, Roya Ayazi-Nasrabadi

Open access · diamondAbstract readReview
In one paragraph

Review in Iranian journal of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Observational
  3. Effects ofAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Small molecules in the treatment of COVID-19.Signal transduction and targeted therapy · 2022
    Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ali-Reza AhmadiDepartment of Biomedical Sciences, Women Research Center, Alzahra University, Tehran, Iran.
Roya Ayazi-NasrabadiDepartment of Biomedical Sciences, Women Research Center, Alzahra University, Tehran, Iran.
Alzahra University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation acts like a double-edged sword and can be harmful if not appropriately controlled. COVID-19 is created through a novel species of coronavirus SARS-CoV-2 (2019-nCoV). Elevated levels of inflammatory factors such as interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), etc. lead to Acute Respiratory Distress Syndrome (ARDS) and severe complications of infection in the lungs of coronavirus-infected patients. Astaxanthin is a natural and potent carotenoid with powerful antioxidant activity as well as an anti-inflammatory agent that supports good health. The effects of astaxanthin on the regulation of cyclooxygenase-2 (COX-2) pathways and the reduction and suppression of cytokines and other inflammatory agents such as IL-6 and TNF-α have already been identified. Therefore, these unique features can make this natural compound an excellent option to minimize inflammation and its consequences.

Indexed as

Anti-inflammatory agentAstaxanthinCOVID-19Interleukin-6Respiratory distress syndromeTumor necrosis factor-alpha

Identifiers

PMID34557270
PMCPMC8421583
OpenAlexW3195139932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.