Evidence map›Paper›PMID 34557235›Full record

ArticleIranian journal of parasitology

Effects of Cytokines IFN-γ and TGF-β on the Functional Activity of Blood Mononuclear Cells against

Maximilian Wilhelm Brune, Eduardo Luzía França, Lucélia Campelo Albuquerque Moraes, Victor Pena Ribeiro, Maria Aparecida Gomes, Adenilda Cristina Honorio-França

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maximilian Wilhelm BruneInstitute of Biological and Health Science, Federal University of Mato Grosso, Barra do Garças, MT, Brazil.
Eduardo Luzía FrançaInstitute of Biological and Health Science, Federal University of Mato Grosso, Barra do Garças, MT, Brazil.
Lucélia Campelo Albuquerque MoraesInstitute of Biological and Health Science, Federal University of Mato Grosso, Barra do Garças, MT, Brazil.
Victor Pena RibeiroInstitute of Biological and Health Science, Federal University of Mato Grosso, Barra do Garças, MT, Brazil.
Maria Aparecida GomesDepartment of Parasitology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Adenilda Cristina Honorio-FrançaInstitute of Biological and Health Science, Federal University of Mato Grosso, Barra do Garças, MT, Brazil.
Universidade Federal de Mato Grosso · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to analyze cultures of mononuclear (MN) cells with

methodsThis study was conducted in 2018 in Barra do Garças, Mato Grosso State, Brazil. Blood samples were collected from 60 healthy volunteer donors to obtain leukocytes. The levels of IFN-γ and TGF-β were quantified in trophozoite cell culture supernatants. Superoxide release, phagocytosis, microbicidal activity, apoptosis and intracellular calcium release were analyzed.

resultsThe cytokines evaluated were detected in the culture supernatant of MN cells and

conclusionCytokines play a beneficial role in the host by activating MN cells against G. lamblia. In addition, phagocytosis causes

Indexed as

CytokinesGiardia lambliaMononuclear cellsPhagocytosis

Identifiers

PMID34557235
PMCPMC8418650
OpenAlexW3170264178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.