Evidence map›Paper›PMID 34557192›Full record

ReviewFrontiers in immunology2021

NAADP: From Discovery to Mechanism.

Timothy F Walseth, Andreas H Guse

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Ryanodine Receptor 1 Is Dispensable for CD4European journal of immunology · 2026
    Article
  3. Putative role of TMEM165 in congenital cardiomyopathies.Frontiers in molecular neuroscience · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. NAADP-Evoked CaInternational journal of molecular sciences · 2023
    Article
  11. T cell CaFrontiers in immunology · 2023
    Review
  12. NAADP-Mediated CaHandbook of experimental pharmacology · 2023
    Article
  13. Article
  14. NAADP-binding proteins find their identity.Trends in biochemical sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Timothy F WalsethDepartment of Pharmacology, University of Minnesota Medical School, Minneapolis, MN, United States.
Andreas H GuseThe Calcium Signalling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Universität Hamburg · DEUniversity of Minnesota Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinic acid adenine dinucleotide 2'-phosphate (NAADP) is a naturally occurring nucleotide that has been shown to be involved in the release of Ca

Indexed as

AnimalsCalciumCalcium ChannelsCalcium SignalingHumansMicrotubule-Associated ProteinsNADPCalciumCalcium ChannelsJPT2 protein, humanMicrotubule-Associated ProteinsNAADPNADPcalcium signalingHN1L/JPT2NAADPryanodine receptortwo-pore channel

Identifiers

PMID34557192
PMCPMC8452981
OpenAlexW3197752561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.