Evidence map›Paper›PMID 34557127›Full record

ArticleFrontiers in psychology2021

Quantifying Voice Characteristics for Detecting Autism.

Meysam Asgari, Liu Chen, Eric Fombonne

Abstract read
In one paragraph

Article in Frontiers in psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Artificial Intelligence Methods in Early Detection of Autism Spectrum Disorder: A DSM-5 Criterion-Based Systematic Review.Autism research : official journal of the International Society for Autism Research · 2026
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. [Artificial intelligence in preventive medicine for children and adolescents-applications and acceptance].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Review
  8. The Sound of Emotional Prosody: Nearly 3 Decades of Research and Future Directions.Perspectives on psychological science : a journal of the Association for Psychological Science · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Detecting autism from picture book narratives using deep neural utterance embeddings.International journal of language & communication disorders · 2022
    Article
  16. Combining voice and language features improves automated autism detection.Autism research : official journal of the International Society for Autism Research · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meysam AsgariInstitute on Development and Disability, Department of Pediatrics, Oregon Health & Science University, Portland, OR, United States.
Liu ChenInstitute on Development and Disability, Department of Pediatrics, Oregon Health & Science University, Portland, OR, United States.
Eric FombonneDepartments of Psychiatry and Pediatrics, Oregon Health & Science University, Portland, OR, United States.

Funding

Computational characterization of language use in autism spectrum disorderR01DC012033 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI FOMBONNE, ERIC · 2011 to 2021
$6.7M
NIDCD NIH HHS R01 DC012033
6 · The paper itself

Abstract

The presence of prosodic anomalies in autistic is recognized by experienced clinicians but their quantitative analysis is a cumbersome task beyond the scope of typical pen and pencil assessment. This paper proposes an automatic approach allowing to tease apart various aspects of prosodic abnormalities and to translate them into fine-grained, automated, and quantifiable measurements. Using a harmonic model (HM) of voiced signal, we isolated the harmonic content of speech and computed a set of quantities related to harmonic content. Employing these measures, along with standard speech measures such as loudness, we successfully trained machine learning models for distinguishing individuals with autism from those with typical development (TD). We evaluated our models empirically on a task of detecting autism on a sample of 118 youth (90 diagnosed with autism and 28 controls; mean age: 10.9 years) and demonstrated that these models perform significantly better than a chance model. Voice and speech analyses could be incorporated as novel outcome measures for treatment research and used for early detection of autism in preverbal infants or toddlers at risk of autism.

Indexed as

autism spectrum disorderharmonic modelmachine learningprosodyspeech analysisvoice

Identifiers

PMID34557127
PMCPMC8452864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.