ArticleFrontiers in physiology2021
Gastrointestinal Assessment and Therapeutic Intervention for the Management of Exercise-Associated Gastrointestinal Symptoms: A Case Series Translational and Professional Practice Approach.
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- A systematic and critical review of measurement scales for evaluating gastrointestinal symptoms during exercise.Journal of the International Society of Sports Nutrition · 2026Pooled it
- Sports Dietitians Australia and Ultra Sports Science Foundation Joint Position Statement: A Practitioner Guide to the Prevention and Management of Exercise-Associated Gastrointestinal Perturbations and Symptoms.Sports medicine (Auckland, N.Z.) · 2025Guideline
- The Influence of Dietary Supplements on Exercise-Induced Gut Damage and Gastrointestinal Symptoms: A Systematic Review and Meta-Analysis.Nutrients · 2025Pooled it
- The Effect of Gut-Training and Feeding-Challenge on Markers of Gastrointestinal Status in Response to Endurance Exercise: A Systematic Literature Review.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Caffeine exacerbates exercise-induced gut cell damage and is influenced by ADORA2A genotype but not CYP1A2 genotype: A preliminary study.Physiological reports · 2025Trial
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- Trial
- Dietary FODMAP Manipulation for Exercise-Associated Gastrointestinal Symptoms: Why Symptom Severity Should Guide Our Approach.Sports medicine (Auckland, N.Z.) · 2026Article
- Exploration of Exercise-Induced Gastrointestinal Syndrome in Endurance-Trained Adolescents: Is There Cause for Concern in Regard to Ultra-endurance Event Participation.Sports medicine - open · 2026Article
- Plant-protein supplementation improves thermoregulatory responses and ameliorates markers of intestinal damage during exercise in the heat.Experimental physiology · 2026Article
- Article
- Fibre: The Forgotten Carbohydrate in Sports Nutrition Recommendations.Sports medicine (Auckland, N.Z.) · 2025Review
- Physical Exercise as a Therapeutic Approach in Gastrointestinal Diseases.Journal of clinical medicine · 2025Review
- The increase in core body temperature in response to exertional-heat stress can predict exercise-induced gastrointestinal syndrome.Temperature (Austin, Tex.) · 2024Article
- Nandrolone decanoate impairs gastrointestinal motility and duodenal morphometry in moderately exercised rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024Article
- Influence of the 2000-m ergometer test on indirect markers of intestinal injury in competitive elite rowers in different training phases.BMC sports science, medicine & rehabilitation · 2023Article
- Reliability of pathophysiological markers reflective of exercise-induced gastrointestinal syndrome (EIGS) in response to 2-h high-intensity interval exercise: A comprehensive methodological efficacy exploration.Frontiers in physiology · 2023Article
- Carbohydrate knowledge, beliefs, and intended practices, of endurance athletes who report exercise-associated gastrointestinal symptoms.Frontiers in nutrition · 2023Article
- The effect of prolonged interval and continuous exercise in the heat on circulatory markers of intestinal barrier integrity.European journal of applied physiology · 2022Article
- Plasma Endogenous Endotoxin Core Antibody Response to Exercise in Endurance Athletes.International journal of sports medicine · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This translational research case series describes the implementation of a gastrointestinal assessment protocol during exercise (GastroAxEx) to inform individualised therapeutic intervention of endurance athletes affected by exercise-induced gastrointestinal syndrome (EIGS) and associated gastrointestinal symptoms (GIS). A four-phase approach was applied. Phase 1: Clinical assessment and exploring background history of exercise-associated gastrointestinal symptoms. Phase 2: Individual tailored GastroAxEx laboratory simulation designed to mirror exercise stress, highlighted in phase 1, that promotes EIGS and GIS during exercise. Phase 3: Individually programmed therapeutic intervention, based on the outcomes of Phase 2. Phase 4: Monitoring and readjustment of intervention based on outcomes from field testing under training and race conditions. Nine endurance athletes presenting with EIGS, and two control athletes not presenting with EIGS, completed Phase 2. Two athletes experienced significant thermoregulatory strain (peak core temperature attained > 40°C) during the GastroAxEx. Plasma cortisol increased substantially pre- to post-exercise in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.