Evidence map›Paper›PMID 34557098›Full record

ArticleFrontiers in pharmacology2021

MLIF Modulates Microglia Polarization in Ischemic Stroke by Targeting eEF1A1.

Yulan Liu, Shanshan Deng, Zhibing Song, Qian Zhang, Yuchen Guo, Yongsheng Yu, Yuliang Wang, Tiejun Li, Fayed A K Megahed, Tamer A Addissouky and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yulan LiuSchool of Medicine, Shanghai University, Shanghai, China.
Shanshan DengSchool of Medicine, Shanghai University, Shanghai, China.
Zhibing SongCollege of Pharmacology, Anhui University of Chinese Medicine, Hefei, China.
Qian ZhangCollege of Pharmacology, Anhui University of Chinese Medicine, Hefei, China.
Yuchen GuoCollege of Pharmacology, Anhui University of Chinese Medicine, Hefei, China.
Yongsheng YuSchool of Medicine, Shanghai University, Shanghai, China.
Yuliang WangJoint International Research Laboratory of Metabolic and Developmental Sciences, Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Tiejun LiSchool of Medicine, Shanghai University, Shanghai, China.
Fayed A K MegahedNucliec Acid Research Departement, Genetic Engineering and Biotechnological Research Institute, City of Scientific Research and Technological Applications, Alexandria, Egypt.
Tamer A AddissoukyMLS Ministry of Health, Alexandria, Egypt.
Junqin MaoDepartment of Clinical Pharmacy, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuefan ZhangSchool of Medicine, Shanghai University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monocyte locomotion inhibitory factor (MLIF) is a heat-stable pentapeptide from

Indexed as

brain ischemiaeukaryotic translation elongation factor 1A1 (eEF1A1)inflammationmicroglia polarizationmonocyte locomotion inhibitory factor (MLIF)

Identifiers

PMID34557098
PMCPMC8452963

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.