Evidence map›Paper›PMID 34557024›Full record

ArticleInternational journal of general medicine2021

Early Pregnancy Glycemic Levels in Non-Diabetic Women and Pregnancy Outcome: A Retrospective Cross-Sectional Study.

Naser Al-Husban, Diala Walid Abu-Hassan, Ayman Qatawneh, Zaid AlSunna, Yasmine Alkhatib, Seif Alnawaiseh, Moyasser Alkhatib, Maysa Yousef

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Naser Al-HusbanDepartment of Obstetrics and Gynecology, School of Medicine, The University of Jordan, Amman, Jordan.ORCID 0000-0002-5896-9848
Diala Walid Abu-HassanDepartment of Physiology and Biochemistry, School of Medicine, The University of Jordan, Amman, Jordan.
Ayman QatawnehDepartment of Obstetrics and Gynecology, School of Medicine, The University of Jordan, Amman, Jordan.
Zaid AlSunnaObstetrics and Gynecology, Jordan University Hospital, Amman, Jordan.ORCID 0000-0002-5911-6556
Yasmine AlkhatibObstetrics and Gynecology, Jordan University Hospital, Amman, Jordan.ORCID 0000-0003-0831-2300
Seif AlnawaisehObstetrics and Gynecology, Jordan University Hospital, Amman, Jordan.
Moyasser AlkhatibObstetrics and Gynecology, Jordan University Hospital, Amman, Jordan.
Maysa YousefObstetrics and Gynecology, Jordan University Hospital, Amman, Jordan.
Jordan Hospital · JOUniversity of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaternal fasting blood sugar (FBS) variations within normal range and lower than that in diabetes mellitus (DM) may be associated with adverse feto-maternal outcomes.

objectiveTo find out if a rise of maternal FBS level above 80 but still below 120 mg/dL (group 2) has an influence on feto-maternal outcomes compared with a maternal FBS below 80 mg/dL (group 1).

methodsRetrospective cross-sectional study. FBS was measured at the booking visit. Subjects whose FBS was measured before 20 weeks were categorized according to their FBS (>80 mg/dL or ≤80 mg/dL) and correlation between FBS levels in the two groups with several parameters were tested.

resultsGroup 1 (130 healthy pregnant women) and group 2 (88 healthy pregnant women) did not show a statistical difference in age or BMI. More statistically significant cases were diagnosed with GDM in group 2 than in group 1 (39.8% vs 16.9%, P value 0.000). More cases that needed pharmacological intervention in the form of metformin or insulin or both were seen in group 2 than in group 1 (p value 0.007 and 0.061, respectively). More but not statistically significant polyhydramnios was seen more in group 2 than in group 1 (9.1% vs 3.1%, p value 0.056). There was no statistically significant difference between the 2 groups in relation to all other fetomaternal outcome parameters that were studied.

conclusionRaised maternal fasting blood glucose level (80-120 mg/dL) in healthy primigravid women in early pregnancy was associated with significant diagnosis of gestational diabetes mellitus and need for pharmacological intervention. An association was found with polyhydramnios but this was not statistically significant. No influence was found on preterm birth, fetal weight, mode of delivery or APGAR score. More attention should be given to FBS levels early in pregnancy to reduce the risk for later complications.

Indexed as

fastingfetomaternalglycemicoutcomepregnancy

Identifiers

PMID34557024
PMCPMC8455101
OpenAlexW3199523368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.