ArticleScientific reports2021
Decreased head circumference at birth associated with maternal tobacco smoke exposure during pregnancy on the Japanese prospective birth cohort study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Chemical Components in the Breast Milk of Passive Smoker Women: A Systematic Review and Health Risks Assessment.Biological trace element research · 2025Pooled it
- Nicotine Exposure During Gestation: From Placental Dysfunction to Long-Term Neurobehavioral Outcomes.Birth defects research · 2026Review
- Cohort profile: The Japan Environment and Children's Study.International journal of epidemiology · 2026Article
- Altered head size at birth is associated with maternal 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in Vietnamese infants.Scientific reports · 2025Article
- Potentially toxic metals in umbilical cord blood as a biomarker for passive smoker women.Scientific reports · 2025Article
- Maternal dietary patterns, breastfeeding duration, and their association with child cognitive function and head circumference growth: A prospective mother-child cohort study.PLoS medicine · 2025Article
- Adherence to Healthy Prepregnancy Lifestyle and Risk of Adverse Pregnancy Outcomes: A Prospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Prenatal Exposure to Tobacco and Childhood Cognition and Behavior: Effect Modification by Maternal Folate Intake and Breastfeeding Duration.Child psychiatry and human development · 2025Article
- Unveiling the hidden risk: paternal smoking and alcohol exposure prior to conception as independent factors for allergic rhinitis in children.Frontiers in pediatrics · 2024Article
- The Assessment of Neonatal Anthropometric Indices Association with Umbilical Cord Blood Zinc and Magnesium Levels.Advanced biomedical research · 2023Article
- The impact of exposure to tobacco smoking and maternal trauma in fetal life on risk of migraine.Frontiers in neuroscience · 2023Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maternal tobacco smoke exposure during pregnancy impairs fetal body size, including head circumference (HC) at birth; however, the mechanism still remains unclear. This analysis using a large prospective cohort study evaluated the impact of maternal tobacco exposure on their offspring's HC and the relationship with placental weight ratio (PWR) and placental abnormalities. Parents-children pairs (n = 84,856) were included from the 104,065 records of the Japan Environmental and Children's Study. Maternal perinatal clinical and social information by self-administered questionnaires, offspring's body size, and placental information were collected. Data were analyzed with binominal logistic regression analysis and path analysis. Logistic regression showed significantly elevated adjusted odds ratio (aOR) (1.653, 95% CI 1.387-1.969) for the impact of maternal smoking during pregnancy on their offspring's smaller HC at birth. Maternal exposure to environmental tobacco smoke in the non-smoking group did not increase aOR for the smaller HC. Path analysis showed that maternal smoking during pregnancy decreased the offspring's HC directly, but not indirectly via PWR or placental abnormalities. The quitting smoking during pregnancy group did not increase aOR for the smaller HC than the non-smoking group, suggesting that quitting smoking may reduce their offspring's neurological impairment even after pregnancy.
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