ArticleScientific reports2021
Metabolomics analysis of grains of wheat infected and noninfected with Tilletia controversa Kühn.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Stepping out of the dark: how metabolomics shed light on fungal biology.FEMS microbiology reviews · 2025Review
- Changes in Metabolomics Profiles ofInternational journal of molecular sciences · 2025Article
- Comparative metabolites analysis of resistant, susceptible and wild rice species in response to bacterial blight disease.BMC plant biology · 2025Article
- Identification and validation of two quantitative trait loci for dwarf bunt in the resistant cultivar 'UI Silver'.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Harnessing multi-omics approaches to combat Karnal bunt of wheat: a review of advances and future prospects.Frontiers in genetics · 2025Review
- Impact of thermal seed treatment on spermosphere microbiome, metabolome and viability of winter wheat.Scientific reports · 2024Article
- Deciphering Aphanomyces euteiches-pea-biocontrol bacterium interactions through untargeted metabolomics.Scientific reports · 2024Article
- Review
- Integrated Transcriptomic and Metabolomic Analyses Identify Critical Genes and Metabolites Associated with Seed Vigor of Common Wheat.International journal of molecular sciences · 2023Article
- Genome Assembly ofInternational journal of molecular sciences · 2023Article
- Decoding Metabolic Reprogramming in Plants under Pathogen Attacks, a Comprehensive Review of Emerging Metabolomics Technologies to Maximize Their Applications.Metabolites · 2023Review
- Unveiling Chemical Interactions Between Plants and Fungi Using Metabolomics Approaches.Advances in experimental medicine and biology · 2023Article
- Integrated metabolomic and transcriptomic analyses of regulatory mechanisms associated with uniconazole-induced dwarfism in banana.BMC plant biology · 2022Article
- Application of Metabolomics in Fungal Research.Molecules (Basel, Switzerland) · 2022Review
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Authors and funding
8 authors.
Funding
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Abstract
Dwarf bunt caused by the pathogen Tilletia controversa Kühn is one of the most serious quarantine diseases of winter wheat. Metabolomics studies provide detailed information about the biochemical changes at the cell and tissue levels of plants. In the present study, a liquid chromatography/mass spectrometry (LC/MS) metabolomics approach was used to investigate the changes in the grain metabolomics of infected and noninfected with T. controversa samples. PCA suggested that T. controversa-infected and noninfected samples were separated during the interaction. LC/MS analysis showed that 62 different metabolites were recorded in the grains, among which a total of 34 metabolites were upregulated and 28 metabolites were downregulated. Prostaglandins (PGs) and 9-hydroxyoctadecadienoic acids (9-HODEs) are fungal toxin-related substances, and their expression significantly increased in T. controversa-infected grains. Additionally, the concentrations of cucurbic acid and octadecatrienoic acid changed significantly after pathogen infection, which play a large role in plant defense. The eight different metabolic pathways activated during T. controversa and wheat plant interactions included phenylalanine metabolism, isoquinoline alkaloid biosynthesis, starch and sucrose metabolism, tyrosine metabolism, sphingolipid metabolism, arginine and proline metabolism, alanine, aspartate, and glutamate metabolism, and tryptophan metabolism. In conclusion, we found differences in the metabolic profiles of wheat grains after T. controversa infection. To our knowledge, this is the first study to evaluate the metabolites in wheat grains after T. controversa infection.
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