Evidence map›Paper›PMID 34556723›Full record

ArticleScientific reports2021

Low serum vitamin D concentrations in Spring-born dairy calves are associated with elevated peripheral leukocytes.

Susana Flores-Villalva, Megan B O'Brien, Cian Reid, Seán Lacey, Stephen V Gordon, Corwin Nelson, Kieran G Meade

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. JDS communications · 2024
    Article
  3. Long-term in vivo vitamin DScientific reports · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Susana Flores-VillalvaAnimal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Grange, Ireland.
Megan B O'BrienAnimal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Grange, Ireland.
Cian ReidAnimal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Grange, Ireland.
Seán LaceyDepartment of Mathematics, Munster Technological University, Cork, Ireland.
Stephen V GordonUCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
Corwin NelsonDepartment of Animal Science, University of Florida, Gainesville, USA.
Kieran G MeadeSchool of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4, Ireland. kieran.meade@ucd.ie.
University College Dublin · IETeagasc - The Irish Agriculture and Food Development Authority · IEMunster Technological University · IEUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A role for vitamin D in the immune system is emerging from human research but data in the bovine is limited. In the current study, 48 Holstein-Friesian calves were randomly assigned to one of 4 groups designed to expose calves to divergent vitamin D levels for a 7 month period and to determine its effects on circulating immunity in young calves. Concentrations of circulating 25-hydroxyvitamin D (25OHD) was measured in serum using a commercial ELISA with validated bovine standards. Results showed that mean circulating concentrations of 25OHD at birth was 7.64 ± 3.21 ng/ml indicating vitamin D deficiency. Neither the injection of Vit D

Indexed as

LeukocytesAnimal FeedAnimalsAnimals, NewbornCattleCholecalciferolDietary SupplementsDisease SusceptibilityLeukocyte CountMaleSeasonsVitamin DVitamin D DeficiencyWeaning25-hydroxyvitamin DCholecalciferolVitamin D

Identifiers

PMID34556723
PMCPMC8460825
OpenAlexW3199847356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.