Evidence map›Paper›PMID 34556710›Full record

Observational studyScientific reports2021

Factors relating to mortality in septic patients in Vietnamese intensive care units from a subgroup analysis of MOSAICS II study.

Son Ngoc Do, Chinh Quoc Luong, Dung Thi Pham, My Ha Nguyen, Nga Thi Nguyen, Dai Quang Huynh, Quoc Trong Ai Hoang, Co Xuan Dao, Trung Minh Le, Ha Nhat Bui and 23 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Son Ngoc Do *Center for Emergency Medicine, Bach Mai Hospital, 78 Giai Phong road, Phuong Mai ward, Dong Da district, Hanoi, 100000, Vietnam.
Chinh Quoc Luong *Center for Emergency Medicine, Bach Mai Hospital, 78 Giai Phong road, Phuong Mai ward, Dong Da district, Hanoi, 100000, Vietnam. luongquocchinh@gmail.com.
Dung Thi PhamDepartment of Nutrition and Food Safety, Faculty of Public Health, Thai Binh University of Medicine and Pharmacy, Thai Binh, 410000, Vietnam.
My Ha NguyenDepartment of Health Organization and Management, Faculty of Public Health, Thai Binh University of Medicine and Pharmacy, Thai Binh, 410000, Vietnam.
Nga Thi NguyenDepartment of Intensive Care and Poison Control, Vietnam-Czechoslovakia Friendship Hospital, Hai Phong, 180000, Vietnam.
Dai Quang HuynhIntensive Care Department, Cho Ray Hospital, Ho Chi Minh City, 700000, Vietnam.
Quoc Trong Ai HoangEmergency Department, Hue Central General Hospital, Hue City, Thua Thien Hue, 530000, Vietnam.
Co Xuan DaoDepartment of Emergency and Critical Care Medicine, Hanoi Medical University, Hanoi, 100000, Vietnam.
Trung Minh LeIntensive Care Unit, 115 People's Hospital, Ho Chi Minh City, 700000, Vietnam.
Ha Nhat BuiIntensive Care Unit, Bai Chay General Hospital, Quang Ninh, 200000, Vietnam.
Hung Tan NguyenIntensive Care Unit, Da Nang Hospital, Da Nang, 550000, Vietnam.
Hai Bui HoangDepartment of Emergency and Critical Care Medicine, Hanoi Medical University, Hanoi, 100000, Vietnam.
Thuy Thi Phuong LeIntensive Care Unit, Dong Da General Hospital, Hanoi, 100000, Vietnam.
Lien Thi Bao NguyenIntensive Care Unit, Saint Paul General Hospital, Hanoi, 100000, Vietnam.
Phuoc Thien DuongIntensive Care Unit, Can Tho Central General Hospital, Can Tho, 900000, Vietnam.
Tuan Dang NguyenIntensive Care Unit, Vinmec Times City International Hospital, Hanoi, 100000, Vietnam.
Yen Hai VuIntensive Care Unit, Da Nang Hospital, Da Nang, 550000, Vietnam.
Giang Thi Tra PhamEmergency Department, Thanh Nhan General Hospital, Hanoi, 100000, Vietnam.
Tam Van BuiDepartment of Intensive Care and Poison Control, Vietnam-Czechoslovakia Friendship Hospital, Hai Phong, 180000, Vietnam.
Thao Thi Ngoc PhamIntensive Care Department, Cho Ray Hospital, Ho Chi Minh City, 700000, Vietnam.
Hanh Trong HoangIntensive Care Unit, Hue Central General Hospital, Hue City, Thua Thien Hue, 530000, Vietnam.
Cuong Van BuiDepartment of Intensive Care, Bach Mai Hospital, Hanoi, 100000, Vietnam.
Nguyen Minh NguyenEmergency and Critical Care Department, Hanoi Medical University Hospital, Hanoi Medical University, Hanoi, 100000, Vietnam.
Giang Thi Huong BuiDepartment of Emergency and Critical Care Medicine, Hanoi Medical University, Hanoi, 100000, Vietnam.
Thang Dinh VuIntensive Care Unit, 115 People's Hospital, Ho Chi Minh City, 700000, Vietnam.
Nhan Duc LeIntensive Care Unit, Da Nang Hospital, Da Nang, 550000, Vietnam.
Trang Huyen TranEmergency and Critical Care Department, Hanoi Medical University Hospital, Hanoi Medical University, Hanoi, 100000, Vietnam.
Thang Quang NguyenIntensive Care Unit, Vinmec Times City International Hospital, Hanoi, 100000, Vietnam.
Vuong Hung LeIntensive Care Unit, Thai Nguyen Central General Hospital, Thai Nguyen, 250000, Vietnam.
Chi Van NguyenCenter for Emergency Medicine, Bach Mai Hospital, 78 Giai Phong road, Phuong Mai ward, Dong Da district, Hanoi, 100000, Vietnam.
Bryan Francis McNallyEmory University Rollins School of Public Health, Atlanta, GA, 30322, USA.
Jason PhuaFAST and Chronic Programmes, Alexandra Hospital, National University Health System, Singapore, 159964, Singapore.
Anh Dat NguyenCenter for Emergency Medicine, Bach Mai Hospital, 78 Giai Phong road, Phuong Mai ward, Dong Da district, Hanoi, 100000, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is the most common cause of in-hospital deaths, especially from low-income and lower-middle-income countries (LMICs). This study aimed to investigate the mortality rate and associated factors from sepsis in intensive care units (ICUs) in an LMIC. We did a multicenter cross-sectional study of septic patients presenting to 15 adult ICUs throughout Vietnam on the 4 days representing the different seasons of 2019. Of 252 patients, 40.1% died in hospital and 33.3% died in ICU. ICUs with accredited training programs (odds ratio, OR: 0.309; 95% confidence interval, CI 0.122-0.783) and completion of the 3-h sepsis bundle (OR: 0.294; 95% CI 0.083-1.048) were associated with decreased hospital mortality. ICUs with intensivist-to-patient ratio of 1:6 to 8 (OR: 4.533; 95% CI 1.621-12.677), mechanical ventilation (OR: 3.890; 95% CI 1.445-10.474) and renal replacement therapy (OR: 2.816; 95% CI 1.318-6.016) were associated with increased ICU mortality, in contrast to non-surgical source control (OR: 0.292; 95% CI 0.126-0.678) which was associated with decreased ICU mortality. Improvements are needed in the management of sepsis in Vietnam such as increasing resources in critical care settings, making accredited training programs more available, improving compliance with sepsis bundles of care, and treating underlying illness and shock optimally in septic patients.

Indexed as

AgedCross-Sectional StudiesFemaleHospital MortalityHumansIntensive Care UnitsMaleMiddle AgedRisk AssessmentRisk FactorsSepsisVietnam

Identifiers

PMID34556710
PMCPMC8460806

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.