ArticleKorean journal of orthodontics2021
Effectiveness of low-level laser therapy and chewing gum in reducing orthodontic pain: A randomized controlled trial.
Article in Korean journal of orthodontics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The effect of pharmacological and non-pharmacological interventions on pain control after orthodontic treatment: a systematic review and network meta-analysis.BMC oral health · 2026Pooled it
- Research Hotspots and Emerging Trends of Orthodontic-Related Discomfort and Pain: A Bibliometric Review.Pain research & management · 2025Pooled it
- The effect of physical interventions on pain control after orthodontic treatment: A systematic review and network meta-analysis.PloS one · 2024Pooled it
- Effect of chewing gum on orthodontic pain in patients receiving fixed orthodontic treatment: a systematic review and meta-analysis.European journal of medical research · 2023Pooled it
- The efficacy of chewing gum in the reduction of orthodontic pain at its peak intensity: a systematic review and meta-analysis.The Angle orthodontist · 2023Pooled it
- A randomized controlled trial on the effectiveness of low-level laser therapy versus paracetamol-caffeine for pain control during overall orthodontic treatment.Scientific reports · 2025Trial
- Effect of single-dose diode laser photobiomodulation on orthodontic pain following initial archwire placement: a randomized clinical trial.BMC oral health · 2025Trial
- Comparative efficacy of pharmaceutical (Ibuprofen) and non-pharmaceutical (photobiomodulation, and chewing gum) interventions for pain reduction after elastomeric separator placement in orthodontic patients: a randomized clinical trial.Lasers in medical science · 2024Trial
- Low-level laser therapy and laser acupuncture therapy for pain relief after initial archwire placement : A randomized clinical trial.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2024Trial
- Review
- Effect of low-level laser therapy on pain reduction in orthodontic patients during molar distalization: A randomized controlled trial.The Saudi dental journal · 2024Article
- Mechanical Vibration and Chewing Gum Methods in Orthodontic Pain Relief.Turkish journal of orthodontics · 2022Article
- The Protocol of Low-level Laser Therapy in Orthodontic Practice: A Scoping Review of Literature.Journal of International Society of Preventive & Community DentistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to evaluate the effects of chewing gum and low-level laser therapy in alleviating orthodontic pain induced by the initial archwire.
methodsPatients with 3-6 mm maxillary crowding who planned to receive non-extraction orthodontic treatment were recruited for the study. Sixty-three participants (33 females and 30 males) were randomly allocated into three groups: laser, chewing gum, and control. In the laser group, a gallium aluminum arsenide (GaAlAs) diode laser with a wavelength of 820 nm was used to apply a single dose immediately after orthodontic treatment began. In the chewing gum group, sugar-free gum was chewed three times for 20 minutes- immediately after starting treatment, and at the twenty-fourth and forty-eighth hours of treatment. Pain perception was measured using a visual analog scale at the second, sixth, and twenty-fourth hours, and on the second, third, and seventh days.
resultsThere were no statistically significant differences between the groups at any measured time point (
conclusionsWithin the limitations of the study, we could not detect whether low-level laser therapy and chewing gum had any clinically significant effect on orthodontic pain. Different results may be obtained with a higher number of participants or using lasers with different wavelengths and specifications. Although the study had a sufficient number of participants according to statistical analysis, higher number of participants could have provided more definitive outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.