ArticleProceedings of the National Academy of Sciences of the United States of America2021
Dim light in the evening causes coordinated realignment of circadian rhythms, sleep, and short-term memory.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- Chronic exposure to LED lighting impairs prefrontal cortex-dependent cognitive functions in adolescent rats.Scientific reports · 2026Article
- Metaplastic sleep regulation inbioRxiv : the preprint server for biology · 2026Article
- Dim light at night disrupts the sleep-wake cycle and exacerbates abnormal EEG activity in Cntnap2 knockout mice: implications for autism spectrum disorders.Molecular autism · 2025Article
- Artificial outdoor light at night and depression in older adults in the USA, England, Northern Ireland, and Ireland.Environment international · 2025Article
- Dissociating the Effects of Light at Night from Circadian Misalignment in a Neurodevelopmental Disorder Mouse Model Using Ultradian Light-Dark Cycles.Clocks & sleep · 2025Article
- Dim light at night induces depression-like behaviors during the postpartum period through circadian rhythm related pathways in mice.Translational psychiatry · 2025Article
- Evaluation of the Digital Ventilated Cage® system for circadian phenotyping.Scientific reports · 2025Article
- Bedtime media use, psychological distress, and fatigue: a study of college students in Shaanxi Province, China.Frontiers in psychology · 2025Article
- Circadian de(regulation) in physiology: implications for disease and treatment.Genes & development · 2024Review
- Beyond Lux: methods for species and photoreceptor-specific quantification of ambient light for mammals.BMC biology · 2024Article
- Phenotypes for general behavior, activity, and body temperature in 3q29 deletion model mice.Translational psychiatry · 2024Article
- Recommendations for measuring and standardizing light for laboratory mammals to improve welfare and reproducibility in animal research.PLoS biology · 2024Article
- Circadian neurogenetics and its implications in neurophysiology, behavior, and chronomedicine.Neuroscience and biobehavioral reviews · 2024Review
- Blue light at night produces stress-evoked heightened aggression by enhancing brain-derived neurotrophic factor in the basolateral amygdala.Neurobiology of stress · 2024Article
- Continuous home cage monitoring of activity and sleep in mice during repeated paroxetine treatment and discontinuation.Psychopharmacology · 2023Article
- Immediate responses to ambient lightiScience · 2023Article
- Associations between light exposure and sleep timing and sleepiness while awake in a sample of UK adults in everyday life.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.Cell death and differentiation · 2023Article
- Translational approaches to influence sleep and arousal.Brain research bulletin · 2022Review
- Cell-Type-Specific Circadian Bioluminescence Rhythms inJournal of biological rhythms · 2022Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
Abstract
Light provides the primary signal for entraining circadian rhythms to the day/night cycle. In addition to rods and cones, the retina contains a small population of photosensitive retinal ganglion cells (pRGCs) expressing the photopigment melanopsin (OPN4). Concerns have been raised that exposure to dim artificial lighting in the evening (DLE) may perturb circadian rhythms and sleep patterns, and OPN4 is presumed to mediate these effects. Here, we examine the effects of 4-h, 20-lux DLE on circadian physiology and behavior in mice and the role of OPN4 in these responses. We show that 2 wk of DLE induces a phase delay of ∼2 to 3 h in mice, comparable to that reported in humans. DLE-induced phase shifts are unaffected in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.