Evidence map›Paper›PMID 34556519›Full record

ArticleBMJ open2021

Seroprevalence of SARS-CoV-2-specific IgG antibodies in Kashmir, India, 7 months after the first reported local COVID-19 case: results of a population-based seroprevalence survey from October to November 2020.

S Muhammad Salim Khan, Mariya Amin Qurieshi, Inaamul Haq, Sabhiya Majid, Javid Ahmad, Taha Ayub, Ashfaq Ahmad Bhat, Anjum Bashir Fazili, Abdul Majeed Ganai, Yasmeen Jan and 24 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Dynamics of SARS-CoV-2 seroassay sensitivity: a systematic review and modelling study.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Community seroprevalence and risk factors for SARS-CoV-2 infection in different subpopulations in Vellore, India, and their implications for future prevention.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 4 institutions in 1 country.

S Muhammad Salim KhanCommunity Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.ORCID 0000-0002-1494-688X
Mariya Amin QurieshiCommunity Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Inaamul HaqCommunity Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India haqinaam@yahoo.co.in.ORCID 0000-0001-8559-8010
Sabhiya MajidBiochemistry, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Javid Ahmad *Community Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
Taha Ayub *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Ashfaq Ahmad Bhat *Community Medicine, SKIMS Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Anjum Bashir Fazili *Community Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
Abdul Majeed Ganai *Community Medicine, Government Medical College Baramulla, Baramulla, Jammu and Kashmir, India.
Yasmeen Jan *Community Medicine, SKIMS Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Rauf-Ur-Rashid Kaul *Community Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
Zahid Ali Khan *Community Medicine, Government Medical College Baramulla, Baramulla, Jammu and Kashmir, India.
Muneer Ahmad Masoodi *Community Medicine, Government Medical College Anantnag, Anantnag, Jammu and Kashmir, India.
Beenish Mushtaq *Community Medicine, SKIMS Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Fouzia Nazir *Community Medicine, Government Medical College Anantnag, Anantnag, Jammu and Kashmir, India.
Muzamil Nazir *Community Medicine, Government Medical College Baramulla, Baramulla, Jammu and Kashmir, India.
Malik Waseem Raja *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Mahbooba Rasool *Community Medicine, Government Medical College Anantnag, Anantnag, Jammu and Kashmir, India.
Anjum Asma *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Shifana Ayoub *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Munazza Aziz *Directorate of Health Services, Government of Jammu and Kashmir, Srinagar, Jammu and Kashmir, India.
Arif Akbar Bhat *Biochemistry, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Iqra Nisar Chowdri *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Shaista Ismail *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Misbah Ferooz Kawoosa *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Mehvish Afzal Khan *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Mosin Saleem Khan *Biochemistry, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Rafiya Kousar *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Ab Aziz Lone *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Shahroz Nabi *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Mohammad Obaid *Biochemistry, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Tanzeela Bashir Qazi *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Iram Sabah *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Ishtiyaq Ahmad Sumji *Community Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashmir, India.
Government Medical College · INSher-i-Kashmir Institute of Medical Sciences · INGovernment College for Women Anantnag · INGovernment Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe designed a population-based survey in Kashmir to estimate the seroprevalence of SARS-CoV-2-specific IgG antibodies in the general population aged 18 years and above.

settingThe survey was conducted among 110 villages and urban wards across 10 districts in Kashmir from 17 October 2020 to 4 November 2020.

participantsIndividuals aged 18 years and above were eligible to be included in the survey. Serum samples were tested for the presence of SARS-CoV-2-specific IgG antibodies using the Abbott SARS-CoV-2 IgG assay. PRIMARY AND SECONDARY OUTCOME MEASURES: We labelled assay results equal to or above the cut-off index value of 1.4 as positive for SARS-CoV-2-specific IgG antibodies. Seroprevalence estimates were adjusted for the sampling design and assay characteristics.

resultsOut of 6397 eligible individuals enumerated, 6315 (98.7%) agreed to participate. The final analysis was done on 6230 participants. Seroprevalence adjusted for the sampling design and assay characteristics was 36.7% (95% CI 34.3% to 39.2%). Seroprevalence was higher among the older population. Among seropositive individuals, 10.2% (247/2415) reported a history of COVID-19-like symptoms. Out of 474 symptomatic individuals, 233 (49.2%) reported having been tested. We estimated an infection fatality rate of 0.034%.

conclusionsDuring the first 7 months of the COVID-19 epidemic in Kashmir Valley, approximately 37% of individuals were infected. The reported number of COVID-19 cases was only a small fraction of the estimated number of infections. A more efficient surveillance system with strengthened reporting of COVID-19 cases and deaths is warranted.

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralHumansImmunoglobulin GSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin GCOVID-19epidemiology

Identifiers

PMID34556519
PMCPMC8461364
OpenAlexW3200893716

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.