Evidence map›Paper›PMID 34556508›Full record

SynthesisBMJ open2021

Health programmes and services addressing the prevention and management of infectious diseases in people who inject drugs in Canada: a systematic integrative review.

Katrina Bouzanis, Siddharth Joshi, Cynthia Lokker, Sureka Pavalagantharajah, Yun Qiu, Hargun Sidhu, Lawrence Mbuagbaw, Majdi Qutob, Alia Henedi, Mitchell A H Levine and 4 more

Abstract readSystematic Review
In one paragraph

Synthesis in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Katrina BouzanisDepartment of Global Health, McMaster University, Hamilton, Ontario, Canada katrina.bouzanis@gmail.com.ORCID 0000-0002-0059-1942
Siddharth JoshiDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Cynthia LokkerDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Sureka PavalagantharajahDepartment of Undergraduate Medical Education, McMaster University, Hamilton, Ontario, Canada.
Yun QiuSchool of Health Sciences, Jiangsu Institute of Commerce, Nanjing, Jiangsu, China.
Hargun SidhuDepartment of Undergraduate Medical Education, McMaster University, Hamilton, Ontario, Canada.
Lawrence MbuagbawDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-5855-5461
Majdi QutobDepartment of Surgery, McMaster University, Hamilton, Ontario, Canada.
Alia HenediFaculty of Pharmacy, Eastern Mediterranean University, Famagusta, North Cyprus, Cyprus.
Mitchell A H LevineDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Robin LennoxDepartment of Family Medicine, McMaster University, Hamilton, Ontario, Canada.
Jean-Eric TarrideDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Dale KalinaDepartment of Infectious Diseases, Hamilton Health Sciences, Hamilton, Ontario, Canada.
Elizabeth AlvarezDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-2333-0144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPeople who inject drugs (PWID) experience a high burden of injection drug use-related infectious disease and challenges in accessing adequate care. This study sought to identify programmes and services in Canada addressing the prevention and management of infectious disease in PWID.

designThis study employed a systematic integrative review methodology. Electronic databases (PubMed, CINAHL and Web of Science Core Collection) and relevant websites were searched for literature published between 2008 and 2019 (last search date was 6 June 2019). Eligible articles and documents were required to address injection or intravenous drug use and health programmes or services relating to the prevention or management of infectious diseases in Canada.

resultsThis study identified 1607 unique articles and 97 were included in this study. The health programmes and services identified included testing and management of HIV and hepatitis C virus (n=27), supervised injection facilities (n=19), medication treatment for opioid use disorder (n=12), integrated infectious disease and addiction programmes (n=10), needle exchange programmes (n=9), harm reduction strategies broadly (n=6), mobile care initiatives (n=5), peer-delivered services (n=3), management of IDU-related bacterial infections (n=2) and others (n=4). Key implications for policy, practice and future research were identified based on the results of the included studies, which include addressing individual and systemic factors that impede care, furthering evaluation of programmes and the need to provide comprehensive care to PWID, involving medical care, social support and harm reduction.

conclusionsThese results demonstrate the need for expanded services across a variety of settings and populations. Our study emphasises the importance of addressing social and structural factors that impede infectious disease care for PWID. Further research is needed to improve evaluation of health programmes and services and contextual factors surrounding accessing services or returning to care. PROSPERO REGISTRATION NUMBER: CRD42020142947.

Indexed as

Communicable DiseasesHepatitis CHIV InfectionsPharmaceutical PreparationsSubstance Abuse, IntravenousHarm ReductionHumansPharmaceutical Preparationshealth policyorganisation of health servicespublic healthsubstance misuse

Identifiers

PMID34556508
PMCPMC8461723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.