Evidence map›Paper›PMID 34556507›Full record

ArticleBMJ open2021

Influence of pre-existing multimorbidity on receiving a hip arthroplasty: cohort study of 28 025 elderly subjects from UK primary care.

Rory Ferguson, Daniel Prieto-Alhambra, George Peat, Antonella Delmestri, Kelvin P Jordan, Vicky Y Strauss, Jose Maria Valderas, Christine Walker, Dahai Yu, Sion Glyn-Jones and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. The projected economic burden and complications of revision hip and knee arthroplasties: Insights from national registry studies.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Review
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Rory FergusonNuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-3256-6434
Daniel Prieto-AlhambraCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-3950-6346
George PeatPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Keele, UK.ORCID 0000-0002-9008-0184
Antonella DelmestriNuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0003-0388-3403
Kelvin P JordanPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Keele, UK.ORCID 0000-0003-4748-5335
Vicky Y StraussCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Jose Maria ValderasHealth Services and Policy Research Group, Medical School, University of Exeter, Exeter, UK.ORCID 0000-0002-9299-1555
Christine WalkerResearch User Group, Primary Care Centre Versus Arthritis, School of Medicine, Keele University, Keele, UK.
Dahai YuPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, Keele, UK.ORCID 0000-0002-8449-7725
Sion Glyn-JonesNuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Alan SilmanNuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK alan.silman@ndorms.ox.ac.uk.ORCID 0000-0001-8426-8925
Nuffield Orthopaedic Centre · GBArthritis UK · GBUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The median age for total hip arthroplasty (THA) is over 70 years with the corollary that many individuals have multiple multimorbidities. Despite the predicted improvement in quality of life, THA might be denied even to those with low levels of multimorbidity.

objectiveTo evaluate how pre-existing levels of multimorbidity influence the likelihood and timing of THA.

settingLongitudinal record linkage study of a UK sample linking their primary care to their secondary care records.

participantsA total of 28 025 patients were included, based on the recording of the diagnosis of hip osteoarthritis in a national primary care register, Clinical Practice Research Datalink. Data were extracted from the database on background health and morbidity status using five different constructs: Charlson Comorbidity Index, Electronic Frailty Index and counts of chronic diseases (from list of 17), prescribed medications and number of primary care visits prior to recording of osteoarthritis. OUTCOME MEASURES: The record of having received a THA as recorded in the primary care record and the linked secondary care database: Hospital Episode Statistics.

results40% had THA: median follow 10 months (range 1-17 years). Increased multimorbidity was associated with a decreased likelihood of undergoing THA, irrespective of the method of assessing multimorbidity although the impact varied by approach.

conclusionMarkers of pre-existing ill health influence the decision for THA in the elderly with end-stage hip osteoarthritis, although these effects are modest for indices of multimorbidity other than eFI. There is evidence of this influence being present even in people with moderate decrements in their health, despite the balance of benefits to risk in these individuals being positive.

Indexed as

Arthroplasty, Replacement, HipOsteoarthritis, HipAgedCohort StudiesHumansMultimorbidityPrimary Health CareQuality of LifeUnited Kingdomgeriatric medicinehealth policyhipsurgery

Identifiers

PMID34556507
PMCPMC8461704
OpenAlexW3199444366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.