ArticleAJNR. American journal of neuroradiology2021
Grading of Pediatric Intracranial Tumors: Are Intravoxel Incoherent Motion and Diffusional Kurtosis Imaging Superior to Conventional DWI?
Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- ADC for Differentiation between Posttreatment Changes and Recurrence in Head and Neck Cancer: A Systematic Review and Meta-analysis.AJNR. American journal of neuroradiology · 2022Pooled it
- Time-dependent Diffusion MRI-based Microstructural Mapping Value for Predicting Meningioma Grade, Subtype, and Proliferative Activity.Radiology. Imaging cancer · 2026Article
- Article
- Diagnostic performance of amide proton transfer-weighted imaging and four advanced diffusion-weighted MRI models for meningioma grading and subtyping.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Whole-tumor histogram analysis of diffusion weighted imaging, diffusion kurtosis imaging, and intravoxel incoherent motion for adult diffuse glioma genotyping.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Perfusion Showdown: Comparison of Multiple MRI Perfusion Techniques in the Grading of Pediatric Brain Tumors.AJNR. American journal of neuroradiology · 2025Article
- Advanced imaging techniques and non-invasive biomarkers in pediatric brain tumors: state of the art.Neuroradiology · 2024Review
- Article
- A Combination of Amide Proton Transfer, Tumor Blood Flow, and Apparent Diffusion Coefficient Histogram Analysis Is Useful for Differentiating Malignant from Benign Intracranial Tumors in Young Patients: A Preliminary Study.Diagnostics (Basel, Switzerland) · 2024Article
- Advanced intraoperative MRI in pediatric brain tumor surgery.Frontiers in physiology · 2023Review
- Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeAn accurate evaluation of the World Health Organization grade is critical in pediatric intracranial tumors. Our aim was to explore the correlations between parameters derived from conventional DWI, intravoxel incoherent motion, and diffusional kurtosis imaging with histopathologic features to evaluate the accuracy of diffusion parameters for grading of pediatric intracranial tumors. MATERIALS AND
methodsFifty-four pediatric patients with histologically proved intracranial tumors who underwent conventional DWI, intravoxel incoherent motion, and diffusional kurtosis imaging were recruited. The conventional DWI (ADC), intravoxel incoherent motion (pure diffusion coefficient [D], pseudodiffusion coefficient [D*], perfusion fraction [f], diffusional kurtosis imaging [K], and diffusion coefficient [Dk]) parameters in the solid component of tumors were measured. The cellularity, Ki-67, and microvessel density were measured. These parameters were compared between the low- and high-grade pediatric intracranial tumors using the Mann-Whitney
resultsThe ADC, D, and Dk values were lower, whereas the K value was higher in high-grade pediatric intracranial tumors than in low-grade tumors (all,
conclusionsIntravoxel incoherent motion- and diffusional kurtosis imaging-derived parameters have similar performance compared with conventional DWI in predicting pediatric intracranial tumor grade. The diffusion metrics may potentially reflect tumor cellularity and Ki-67 in pediatric intracranial tumors.
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