Evidence map›Paper›PMID 34556391›Full record

ArticleThe American journal of emergency medicine2022

Tension pneumomediastinum from opioid inhalation.

Rahul V Nene, Adam T Hryniewicki, Elizabeth Roderick, Scott Chicotka, Moises Hernandez Vazquez, Patricia A Thistlewaite, Christanne Coffey, Mazen F Odish

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rahul V NeneDepartment of Emergency Medicine, University of California San Diego, San Diego, CA, USA. Electronic address: rnene@ucsd.edu.
Adam T HryniewickiDepartment of Emergency Medicine, University of California San Diego, San Diego, CA, USA.
Elizabeth RoderickDepartment of Surgery, Division of Cardiovascular and Thoracic Surgery, University of California San Diego, San Diego, California, USA.
Scott ChicotkaDepartment of Surgery, Division of Cardiovascular and Thoracic Surgery, University of California San Diego, San Diego, California, USA.
Moises Hernandez VazquezDepartment of Surgery, Division of Cardiovascular and Thoracic Surgery, University of California San Diego, San Diego, California, USA.
Patricia A ThistlewaiteDepartment of Surgery, Division of Cardiovascular and Thoracic Surgery, University of California San Diego, San Diego, California, USA.
Christanne CoffeyDepartment of Emergency Medicine, University of California San Diego, San Diego, CA, USA.
Mazen F OdishDepartment of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of California San Diego, San Diego, CA, USA.

Funding

Interdisciplinary Anesthesiology Research Training ProgramT32GM121318 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Hemal H Patel, DAVID M ROTH · 2017 to 2026
$1.5M
NIGMS NIH HHS T32 GM121318
6 · The paper itself

Abstract

Pneumomediastinum is a rare complication of substance use, likely due to a Valsalva maneuver after drug inhalation. There are no previously documented associations between pneumomediastinum and opioid use. A 30-year-old man with a history of recent heroin and fentanyl inhalation presented to the emergency department in respiratory distress requiring intubation. His course was complicated by pneumomediastinum which subsequently developed tension physiology. He required emergent surgical decompression with a "blowhole incision" to his anterior chest. Although a rare complication of polysubstance use, pneumomediastinum can progress to tension physiology, requiring prompt diagnosis and management.

Indexed as

Heroin DependenceMediastinal EmphysemaAdministration, InhalationAdultDyspneaFentanylHumansMaleValsalva ManeuverFentanyl

Identifiers

PMID34556391
PMCPMC8844270

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.