Evidence map›Paper›PMID 34556244›Full record

ReviewDermatologic clinics2021

The Use of Biologics During the COVID-19 Pandemic.

Madison E Jones, Alison H Kucharik, Sarah P Pourali, Jeffrey R Rajkumar, Yasmin Gutierrez, Rebecca M Yim, April W Armstrong

Open access · greenAbstract readReview
In one paragraph

Review in Dermatologic clinics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Madison E JonesUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Alison H KucharikFlorida Atlantic University Charles E Schmidt College of Science, 777 Glades Road BC-71, Boca Raton, FL 33431, USA.
Sarah P PouraliVanderbilt University School of Medicine, 1161 21st Ave S # D3300, Nashville, TN 37232, USA.
Jeffrey R RajkumarUniveristy of Illinois College of Medicine at Chicago, 1853 W Polk St, Chicago, IL 60612, USA.
Yasmin GutierrezUniversity of California Riverside School of Medicine, 92521 Botanic Gardens Dr, Riverside, CA 92507, USA.
Rebecca M YimUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA.
April W ArmstrongUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA. Electronic address: armstrongpublication@gmail.com.
University of Southern California · USFlorida Atlantic University · USUniversity of California, Riverside · USUniversity of Illinois Chicago · USVanderbilt University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the coronavirus disease 2019 (COVID-19) pandemic, there has been considerable discussion regarding the use of biologics in patients with inflammatory skin conditions, such as psoriasis, hidradenitis suppurativa, and atopic dermatitis. This article discusses clinical trial data, real-world evidence, and guidelines and recommendations for biologics that inhibit tumor necrosis factor, interleukin (IL)-12/23, IL-17, IL-23, and IL-4/13 during the COVID-19 pandemic. Across these inflammatory skin conditions, existing data generally suggest that biologics do not seem to increase the risk of COVID-19 infection or worsen COVID-19 outcomes. The impact of biologics on COVID-19 is an area of active exploration.

Indexed as

COVID-19 Drug TreatmentBiological ProductsCOVID-19Dermatitis, AtopicHumansSkin DiseasesBiological ProductsAtopic dermatitisBiologicsCOVID-19DupilumabHidradenitis suppurativaIL inhibitorPsoriasisTNF-Inhibitor

Identifiers

PMID34556244
PMCPMC8166518
OpenAlexW3168141001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.