Evidence map›Paper›PMID 34556160›Full record

ArticleBMC research notes2021

Large dependency of intracellular NAD and CoA pools on cultivation conditions in Saccharomyces cerevisiae.

Kanhaiya Kumar, Per Bruheim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Tryptophan extends the life of cytochrome P450.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kanhaiya KumarDepartment of Biotechnology and Food Science, Norwegian University of Science and Technology, Sem Sælands vei 6/8, N-7491, Trondheim, Norway.
Per BruheimDepartment of Biotechnology and Food Science, Norwegian University of Science and Technology, Sem Sælands vei 6/8, N-7491, Trondheim, Norway. Per.Bruheim@ntnu.no.ORCID http://orcid.org/0000-0002-7851-8083
Norwegian University of Science and Technology · NO

Funding

norges forskningsråd 237165norges forskningsråd 248885
6 · The paper itself

Abstract

objectiveThe objective of this study was to investigate the variation of NAD and CoA metabolite pools in Saccharomyces cerevisiae cultivated under various cultivation conditions. This study complements a previous report on glycolytic, pentose phosphate pathway, tricarboxylic acid cycle, amino acids, and deoxy-/nucleoside phosphate pools determined under the same cultivation conditions.

resultsS. cerevisiae pellets from batch (four carbohydrate sources) and chemostat (carbon-, nitrogen-, phosphate-limited and a range of dilution rates) bioreactor cultivations were extracted and analyzed with two recently established absolute quantitative liquid chromatography mass spectrometry (LC-MS/MS) methods for NAD and CoA metabolites. Both methods apply

Indexed as

NADSaccharomyces cerevisiaeChromatography, LiquidCoenzyme ATandem Mass SpectrometryCoenzyme ANAD13C internal standardBioreactorCoAMass spectrometryMetabolomicsNADSaccharomyces cerevisiae

Identifiers

PMID34556160
PMCPMC8461857
OpenAlexW3200454922

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.