Evidence map›Paper›PMID 34556049›Full record

ArticleBMC nephrology2021

Prevalence and risk factors of chronic kidney disease in an HIV positive Mexican cohort.

Verónica Valdivia-Cerda, Monserrat Alvarez-Zavala, Karina Sánchez-Reyes, Rodolfo I Cabrera-Silva, Vida V Ruiz-Herrera, Aldo D Loza-Salazar, Pedro Martínez-Ayala, Juan C Vázquez-Limón, Guillermo García-García, Jaime F Andrade-Villanueva and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  15. HIV and Substance Use in Latin America: A Scoping Review.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Verónica Valdivia-CerdaServicio de Nefrología, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jalisco, Mexico.
Monserrat Alvarez-ZavalaUniversidad de Guadalajara, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Centro Universitario de Ciencias de La Salud, Jalisco, México.
Karina Sánchez-ReyesUniversidad de Guadalajara, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Centro Universitario de Ciencias de La Salud, Jalisco, México.
Rodolfo I Cabrera-SilvaUniversidad de Guadalajara, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Centro Universitario de Ciencias de La Salud, Jalisco, México.
Vida V Ruiz-HerreraHospital Civil de Guadalajara "Fray Antonio Alcalde", Unidad de VIH, Guadalajara, Jalisco, Mexico.
Aldo D Loza-SalazarHospital Civil de Guadalajara "Fray Antonio Alcalde", Unidad de VIH, Guadalajara, Jalisco, Mexico.
Pedro Martínez-AyalaHospital Civil de Guadalajara "Fray Antonio Alcalde", Unidad de VIH, Guadalajara, Jalisco, Mexico.
Juan C Vázquez-LimónHospital Civil de Guadalajara "Fray Antonio Alcalde", Unidad de VIH, Guadalajara, Jalisco, Mexico.
Guillermo García-GarcíaServicio de Nefrología, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jalisco, Mexico.
Jaime F Andrade-VillanuevaUniversidad de Guadalajara, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Centro Universitario de Ciencias de La Salud, Jalisco, México.
Luz A González-HernándezUniversidad de Guadalajara, Instituto de Investigación en Inmunodeficiencias y VIH (InIVIH), Centro Universitario de Ciencias de La Salud, Jalisco, México. luceroga08@gmail.com.
Hospital Civil de Guadalajara · MXUniversidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV subjects have several kidney pathologies, like HIV-associated nephropathy or antiretroviral therapy injury, among others. The global prevalence of Chronic Kidney Disease (CKD) is 8-16%; however, in HIV subjects, the prevalence varies between geographic regions (2-38%). The aim was to determine the prevalence of CKD and identify the associated risk factors.

methodsA longitudinal descriptive study was carried out at the 'Hospital Civil de Guadalajara' Feb'18 - Jan'19. Basal clinical, demographic, opportunistic infections (OI), and laboratory data were obtained at months 0 and 3; inclusion criteria were ≥ 18 years old, naïve HIV + , urine albumin/creatinine ratio, serum creatinine & urine test, and signed informed consent. Descriptive and multiple logistic regression statistical analyses were made.

resultsOne hundred twenty subjects were included; 92.5% were male, 33 ± 9.5 years, 60% consumed tobacco, 73% alcohol, and 59% some type of drug. The CKD prevalence was 15.8%. CKD patients had a higher risk of hepatitis C virus coinfection, Relative Risk (RR):5.9; HCV infection, RR:4.3; ≥ 30 years old, RR:3.9; C clinical-stage, RR:3.5; CD4

conclusionsOur study showed a higher CKD prevalence in patients with HIV; higher CKD development with coinfections as Hepatitis C Virus and Mycobacterium tuberculosis. The identification and prompt management of CKD and coinfections should be considered to avoid the progression and to delay renal replacement therapy as long as possible.

Indexed as

HIV-1AdultAIDS-Associated NephropathyCD4-CD8 RatioCD4 Lymphocyte CountCoinfectionFemaleHIV SeropositivityHumansMaleMexicoPrevalenceRenal Insufficiency, ChronicRisk FactorsViral LoadAntiretroviral therapyChronic kidney diseaseHIV-positiveMexican cohort

Identifiers

PMID34556049
PMCPMC8461868
OpenAlexW3199279811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.