Observational studyBMC cardiovascular disorders2021
Sex and age difference in risk factor distribution, trend, and long-term outcome of patients undergoing isolated coronary artery bypass graft surgery.
Observational study in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Sex-related differences in long-term mortality after coronary artery bypass graft surgery: A systematic review and meta-analysis.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Fast-Track Extubation After Cardiac Surgery: A Narrative Review.Journal of cardiovascular development and disease · 2025Review
- Comparing Hospital-Free Days by Frailty Status for Patients Undergoing Surgical Intervention for Cardiovascular Disease.Journal of the American College of Surgeons · 2025Article
- Predicting Factors Affecting Survival Rate in Patients Undergoing On-Pump Coronary Artery Bypass Graft Surgery Using Machine Learning Methods: A Systematic Review.Health science reports · 2025Review
- Association between postoperative atrial fibrillation after coronary artery bypass grafting and short-term clinical outcomes.BMC cardiovascular disorders · 2024Article
- Dynamics of the State of Arterial Stiffness as a Possible Pathophysiological Factor of Unfavorable Long-Term Prognosis in Patients after Coronary Artery Bypass Grafting.Biomedicines · 2024Article
- Article
- Sex differences in outcomes of patients undergoing on-pump coronary artery bypass grafting surgery.PloS one · 2024Observational
- Sex differences in the management and outcome of acute coronary syndrome-Still an issue of equal treatment?Wiener klinische Wochenschrift · 2023Review
- Comparison of in-hospital outcomes after coronary artery bypass graft surgery in elders and younger patients: a multicenter retrospective study.Journal of cardiothoracic surgery · 2023Article
- Differences in gender and outcomes following isolated coronary artery bypass graft (CABG) surgery.ARYA atherosclerosis · 2023Article
- Impact of gender on outcomes following single-level anterior lumbar interbody fusion.Journal of clinical orthopaedics and trauma · 2022Article
- Long-Term Prognosis after Coronary Artery Bypass Grafting: The Impact of Arterial Stiffness and Multifocal Atherosclerosis.Journal of clinical medicine · 2022Article
- Early Outcomes of a High PaOThe journal of Tehran Heart Center · 2022Article
- Machine learning algorithms for predicting mortality after coronary artery bypass grafting.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreoperative coronary artery disease risk factors (CADRFs) distribution and pattern may also have an important role in determining major adverse cardiovascular events (MACEs). In this study, we aimed to evaluate the CADRFs distribution and trend over 10 years and also the long-term outcome of CABG in different age-sex categories.
methodIn this registry-based serial cross-sectional study, we enrolled 24,328 patients who underwent isolated CABG and evaluated the prevalence of CADRFs according to sex and age. We used inverse probability weighting (IPW) to compare survival and MACE between the sexes. We also used Cox regression to determine each CADRFs effect on survival and MACEs.
resultsIn general, DLP (56.00%), HTN (53.10%), DM (38.40%), and positive family history (38.30%) were the most frequent risk factors in all patients. Prevalence of HTN, DLP, DM, obesity, and positive family history were all higher in women, all statistically significant. The median follow-up duration was 78.1 months (76.31-79.87 months). After inverse probability weighting (to balance risk factors and comorbidities), men had lower MACEs during follow-up (HR 0.72; 95% CI 0.57-0.91; P value 0.006) and there was no significant difference in survival between sexes. DM and HTN were associated with higher mortality and MACEs in both sexes.
conclusionAlthough DLP is still the most frequent CADRF among the CABG population, the level of LDL and TG is decreasing. Women experience higher MACE post CABG. Therefore, health care providers and legislators must pay greater attention to female population CADRFs and ways to prevent them at different levels.
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