Evidence map›Paper›PMID 34555890›Full record

ArticlePsychiatry investigation2021

Heart Rate Variability and Its Ability to Detect Worsening Suicidality in Adolescents: A Pilot Trial of Wearable Technology.

David C Sheridan, Steven Baker, Ryan Dehart, Amber Lin, Matthew Hansen, Larisa G Tereshchenko, Nancy Le, Craig D Newgard, Bonnie Nagel

Abstract read
In one paragraph

Article in Psychiatry investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  5. Integrating Heart Rate Variability Improves Machine Learning-based Prediction of Panic Disorder Symptom Severity.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David C SheridanDepartment of Emergency Medicine, Oregon Health & Science University, Oregon, USA.
Steven BakerDepartment of Emergency Medicine, Oregon Health & Science University, Oregon, USA.
Ryan DehartDepartment of Emergency Medicine, Oregon Health & Science University, Oregon, USA.
Amber LinDepartment of Emergency Medicine, Oregon Health & Science University, Oregon, USA.
Matthew HansenDepartment of Emergency Medicine, Oregon Health & Science University, Oregon, USA.
Larisa G TereshchenkoDepartment of Medicine, Division of Cardiology, Oregon Health & Science University, Oregon, USA.
Nancy LeDepartment of Emergency Medicine, Oregon Health & Science University, Oregon, USA.
Craig D NewgardDepartment of Emergency Medicine, Oregon Health & Science University, Oregon, USA.
Bonnie NagelDepartment of Psychiatry, Oregon Health & Science University, Oregon, USA.

Funding

Oregon Emergency Care Research Multidisciplinary Training ProgramK12HL133115 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MORRIS, CYNTHIA D, NEWGARD, CRAIG D. · 2016 to 2020
$2.9M
Novel ECG measures and risk of sudden cardiac deathR56HL118277 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TERESHCHENKO, LARISA GENNADIEVNA · 2018 to 2018
$396k
NHLBI NIH HHS K12 HL133115NHLBI NIH HHS R56 HL118277NIH HHS 5K12HL133115NIMH NIH HHS K12
6 · The paper itself

Abstract

objectiveSuicide is the 2nd leading cause of death in adolescence, and acute pediatric mental health emergency department (ED) visits have doubled in the past decade. The objective of this study was to evaluate physiologic parameters relationship to suicide severity.

methodsThis was a prospective, observational study from April 2018 thru November 2019 in a tertiary care pediatric emergency department (ED) and inpatient pediatric psychiatric unit enrolling acutely suicidal adolescent patients. Patients wore a wrist device that used photoplethysmography for 7 days during their acute hospitalization to measure heart rate variability (HRV). During that time, Columbia Suicide Severity Scores (CSSRS) were assessed at 3 time points.

resultsThere was complete device data and follow-up for 51 patients. There was an increase in the high frequency (HF) component of HRV in patients that had a 25% or greater decrease in their CSSRS (mean difference 11.89 ms/ Hz ; p-value 0.005). Patients with a CSSRS≥15 on day of enrollment had a lower, although not statistically significant, HF component (mean difference -8.34 ms/ Hz; p-value 0.071).

conclusionWe found an inverse correlation between parasympathetic activity measured through the HF component and suicidality in an acutely suicidal population of adolescents. Wearable technology may have the ability to improve outpatient monitoring for earlier detection and intervention.

Indexed as

Child and adolescence psychiatryDepressive disorderSuicide

Identifiers

PMID34555890
PMCPMC8542751

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.