ArticleBrain and language2021
Neural bases of elements of syntax during speech production in patients with aphasia.
Article in Brain and language, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Distinct Patterns of Syntactic Errors Doubly Dissociate in Chronic Poststroke Aphasia.Journal of cognitive neuroscience · 2026Article
- Spatiotemporal dynamics of lexical and morphosyntactic planning during language production revealed by magnetoencephalography.bioRxiv : the preprint server for biology · 2026Article
- From structure to sequence: A multinomial processing tree model of syntactic encoding.Psychonomic bulletin & review · 2026Article
- Acute-Phase Machine Learning Prediction of 12-Month Aphasia and Discourse Recovery.medRxiv : the preprint server for health sciences · 2026Article
- Influence of lexical and phonological variables on the production of verb tense in agrammatism.Aphasiology · 2025Article
- Data-driven classification of narrative speech characteristics in stroke aphasia distinguishes neurological and strategic contributions.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Partial least squares multimodal analysis of brain network correlates of language deficits in aphasia.Brain communications · 2025Article
- Neural Predictors for the Generalization of Semantic and Phonological Treatment to Discourse Performance in Chronic Post-Stroke Aphasia.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Connected Speech Fluency in Poststroke and Progressive Aphasia: A Scoping Review of Quantitative Approaches and Features.American journal of speech-language pathology · 2024Article
- Discriminating nonfluent/agrammatic and logopenic PPA variants with automatically extracted morphosyntactic measures from connected speech.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- A reconceptualization of sentence production in post-stroke agrammatic aphasia: the synergistic processing bottleneck model.Frontiers in language sciences · 2023Article
- Cortical and structural-connectivity damage correlated with impaired syntactic processing in aphasia.Human brain mapping · 2019Article
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Authors and funding
11 authors at 5 institutions in 1 country.
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Abstract
The ability to string together words into a structured arrangement capable of conveying nuanced information is key to speech production. The assessment of the neural bases for structuring sentences has been challenged by the need of experts to delineate the aberrant morphosyntactic structures in aphasic speech. Most studies have relied on focused tasks with limited ecological validity. We characterized syntactic complexity during connected speech produced by patients with chronic post-stroke aphasia. We automated this process by employing Natural Language Processing (NLP). We conducted voxel-based and connectome-based lesion-symptom mapping to identify brain regions crucially associated with sentence production and syntactic complexity. Posterior-inferior aspects of left frontal and parietal lobes, as well as white matter tracts connecting these areas, were essential for syntactic complexity, particularly the posterior inferior frontal gyrus. These findings suggest that sentence structuring during word production depends on the integrity of Broca's area and the dorsal stream of language processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.