Evidence map›Paper›PMID 34555661›Full record

ArticleMedical image analysis2021

Using synthetic data generation to train a cardiac motion tag tracking neural network.

Michael Loecher, Luigi E Perotti, Daniel B Ennis

Abstract read
In one paragraph

Article in Medical image analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Feasibility of tagged MRI at 0.55 T.Magnetic resonance in medicine · 2026
    Article
  3. Article
  4. Review
  5. DeepMesh: Mesh-Based Cardiac Motion Tracking Using Deep Learning.IEEE transactions on medical imaging · 2024
    Article
  6. Article
  7. Article
  8. Highly accelerated free-breathing real-time myocardial tagging for exercise cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  9. MRXCAT2.0: Synthesis of realistic numerical phantoms by combining left-ventricular shape learning, biophysical simulations and tissue texture generation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Quantification of exercised-induced myocardial deformation with exercise CMR.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael LoecherDepartment of Radiology, Stanford University, USA. Electronic address: mloecher@stanford.edu.
Luigi E PerottiDepartment of Mechanical and Aerospace Engineering, University of Central Florida, USA.
Daniel B EnnisDepartment of Radiology, Stanford University, USA; Cardiovascular Institute, Stanford University, USA; Center for Artificial Intelligence in Medicine & Imaging, Stanford University, USA.

Funding

Using Atrial Mechanics To Identify Fibrosis In Patients with Atrial FibrillationR01HL152256 · NHLBI · STANFORD UNIVERSITY · PI ENNIS, DANIEL B · 2020 to 2023
$2.8M
Validating Cardiac MRI Biomarkers and Genotype-Phenotype Correlations for DMDR01HL131975 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ENNIS, DANIEL B · 2016 to 2019
$2.5M
A New Framework for Understanding the Mechanisms of Diastolic DysfunctionR01HL131823 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ENNIS, DANIEL B · 2017 to 2020
$2.3M
NHLBI NIH HHS R01 HL131823NHLBI NIH HHS R01 HL131975NHLBI NIH HHS R01 HL152256
6 · The paper itself

Abstract

A CNN based method for cardiac MRI tag tracking was developed and validated. A synthetic data simulator was created to generate large amounts of training data using natural images, a Bloch equation simulation, a broad range of tissue properties, and programmed ground-truth motion. The method was validated using both an analytical deforming cardiac phantom and in vivo data with manually tracked reference motion paths. In the analytical phantom, error was investigated relative to SNR, and accurate results were seen for SNR>10 (displacement error <0.3 mm). Excellent agreement was seen in vivo for tag locations (mean displacement difference = -0.02 pixels, 95% CI [-0.73, 0.69]) and calculated cardiac circumferential strain (mean difference = 0.006, 95% CI [-0.012, 0.024]). Automated tag tracking with a CNN trained on synthetic data is both accurate and precise.

Indexed as

Magnetic Resonance ImagingNeural Networks, ComputerComputer SimulationHeartHumansMotionPhantoms, ImagingCardiac MRIConvolutional neural networkMachine learningSynthetic dataTag tracking

Identifiers

PMID34555661
PMCPMC8560564

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.