Evidence map›Paper›PMID 34555069›Full record

ArticlePloS one2021

Predicting fracture outcomes from clinical registry data using artificial intelligence supplemented models for evidence-informed treatment (PRAISE) study protocol.

Joanna F Dipnall, Richard Page, Lan Du, Matthew Costa, Ronan A Lyons, Peter Cameron, Richard de Steiger, Raphael Hau, Andrew Bucknill, Andrew Oppy and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Joanna F DipnallClinical Registries, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-7543-0687
Richard PageSchool of Medicine, Deakin University, St. John of God Hospital, University Hospital Geelong, Geelong, Victoria, Australia.
Lan DuDepartment of Data Science & AI, Faculty of Information Technology, Monash University, Clayton, Victoria, Australia.ORCID 0000-0002-9925-0223
Matthew CostaOxford Trauma and Emergency Care, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.
Ronan A LyonsClinical Registries, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Peter CameronDepartment of Epidemiology & Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Richard de SteigerDepartment of Surgery, University of Melbourne, Epworth HealthCare, Epworth, Richmond, Victoria, Australia.
Raphael HauEastern Health Clinical School, Monash University, Box Hill, Victoria, Australia.
Andrew BucknillDepartment of Orthopaedic Surgery, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Andrew OppyDepartment of Orthopaedic Surgery, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Elton EdwardsDepartment of Epidemiology & Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Dinesh VarmaDepartment of Surgery, Monash University, Melbourne, Australia.
Myong Chol JungClinical Registries, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Belinda J GabbeClinical Registries, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-7096-7688
The Alfred Hospital · AUDeakin University · AUMonash University · AUSwansea University · GBThe Royal Melbourne Hospital · AUEastern Health · AUNuffield Orthopaedic Centre · GBThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDistal radius (wrist) fractures are the second most common fracture admitted to hospital. The anatomical pattern of these types of injuries is diverse, with variation in clinical management, guidelines for management remain inconclusive, and the uptake of findings from clinical trials into routine practice limited. Robust predictive modelling, which considers both the characteristics of the fracture and patient, provides the best opportunity to reduce variation in care and improve patient outcomes. This type of data is housed in unstructured data sources with no particular format or schema. The "Predicting fracture outcomes from clinical Registry data using Artificial Intelligence (AI) Supplemented models for Evidence-informed treatment (PRAISE)" study aims to use AI methods on unstructured data to describe the fracture characteristics and test if using this information improves identification of key fracture characteristics and prediction of patient-reported outcome measures and clinical outcomes following wrist fractures compared to prediction models based on standard registry data. METHODS AND

designAdult (16+ years) patients presenting to the emergency department, treated in a short stay unit, or admitted to hospital for >24h for management of a wrist fracture in four Victorian hospitals will be included in this study. The study will use routine registry data from the Victorian Orthopaedic Trauma Outcomes Registry (VOTOR), and electronic medical record (EMR) information (e.g. X-rays, surgical reports, radiology reports, images). A multimodal deep learning fracture reasoning system (DLFRS) will be developed that reasons on EMR information. Machine learning prediction models will test the performance with/without output from the DLFRS. DISCUSSION: The PRAISE study will establish the use of AI techniques to provide enhanced information about fracture characteristics in people with wrist fractures. Prediction models using AI derived characteristics are expected to provide better prediction of clinical and patient-reported outcomes following distal radius fracture.

Indexed as

Evidence-Based MedicineFracture HealingAdolescentAdultAlgorithmsArtificial IntelligenceData ManagementElectronic Health RecordsFracture FixationHumansOrthopedicsPatient Reported Outcome MeasuresRadius FracturesRegistriesVictoriaWrist Injuries

Identifiers

PMID34555069
PMCPMC8460020
OpenAlexW3200391510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.