Evidence map›Paper›PMID 34554830›Full record

ArticleJCO oncology practice2022

Incorporating Reproductive Health in the Clinical Management of Early-Onset Colorectal Cancer.

Andreana N Holowatyj, Cathy Eng, Mark A Lewis

Registry-linked trialAbstract readEditorial
In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05239338 (Preserving Fertility After Colorectal Cancer), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05239338 recruitingnot on this map

Preserving Fertility After Colorectal Cancer: The PREFACE Study

TypeobservationalSponsorAndreana Holowatyj, PhD, MSCIRan2021 to 2037Enrolled1,000ConditionsColorectal Cancer
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Guideline
  2. Review
  3. Early-Onset Colorectal Cancer: From Genetic Discovery to Clinical Innovation.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2025
    Review
  4. The Young: Early-Onset Colon Cancer.Clinics in colon and rectal surgery · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Cancer treatment and survivorship statistics, 2025.CA: a cancer journal for clinicians
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andreana N HolowatyjDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0001-8001-8793
Cathy EngDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0003-2335-0612
Mark A LewisIntermountain Healthcare, Murray, UT.ORCID 0000-0001-8633-6557

Funding

Building Interdisciplinary Research Careers in Women's HealthK12HD043483 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARTMANN, KATHERINE E, MAJOR, AMY S · 2002 to 2023
$10.3M
NICHD NIH HHS K12 HD043483
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colorectal NeoplasmsReproductive HealthHumans

Identifiers

PMID34554830
PMCPMC8932489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.