Evidence map›Paper›PMID 34554825›Full record

ArticleJCO clinical cancer informatics2021

Data Matching to Support Analysis of Cancer Epidemiology Among Veterans Compared With Non-Veteran Populations-An Exemplar in Brain Tumors.

Christine Woo, Gino N Cioffi, Taissa A Bej, Brigid Wilson, Janet M Briggs, Sarah C Markt, Fredrick R Schumacher, Carol Kruchko, Kristin A Waite, L Burt Nabors and 3 more

Open access · hybridAbstract read
In one paragraph

Article in JCO clinical cancer informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Christine WooHealthcare Leadership Talent Institute, Veterans Health Administration, Cleveland, OH.
Gino N CioffiNational Cancer Institute, Division of Cancer Epidemiology and Genetics, Trans-Divisional Research Program, Bethesda, MD.
Taissa A BejGeriatric Research Education and Clinical Center (GRECC), Veterans Affairs Northeast Ohio Healthcare System, Cleveland, OH.ORCID 0000-0002-4797-1432
Brigid WilsonGeriatric Research Education and Clinical Center (GRECC), Veterans Affairs Northeast Ohio Healthcare System, Cleveland, OH.
Janet M BriggsGeriatric Research Education and Clinical Center (GRECC), Veterans Affairs Northeast Ohio Healthcare System, Cleveland, OH.
Sarah C MarktDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH.ORCID 0000-0003-2873-0358
Fredrick R SchumacherDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH.ORCID 0000-0002-3073-7463
Carol KruchkoCentral Brain Tumor Registry of the United States (CBTRUS), Hinsdale, IL.
Kristin A WaiteNational Cancer Institute, Division of Cancer Epidemiology and Genetics, Trans-Divisional Research Program, Bethesda, MD.
L Burt NaborsDivision of Neuro-oncology, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0001-5926-2230
Charles J NockHematology and Oncology Section, Veterans Affairs Northeast Ohio Healthcare System, Cleveland, OH.
Robin L P JumpGeriatric Research Education and Clinical Center (GRECC), Veterans Affairs Northeast Ohio Healthcare System, Cleveland, OH.ORCID 0000-0001-5601-8996
Jill S Barnholtz-SloanNational Cancer Institute, Division of Cancer Epidemiology and Genetics, Trans-Divisional Research Program, Bethesda, MD.ORCID 0000-0001-6190-9304
Central Brain Tumor Registry of the United States · USGeriatric Research Education and Clinical Center · USCase Western Reserve University · USKent State University · USUniversity Health System · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeState and national cancer registries do not systematically include Veteran data, which hinders analysis of the diagnosis patterns, treatment trajectories, and clinical outcomes of Veterans compared with non-Veteran populations. This study used data matching approaches to compare cases included in the Oncology Domain of the Veterans Affairs (VA) Corporate Data Warehouse and the Ohio Cancer Incidence Surveillance System, using brain tumors as an exemplar.

methodsWe used direct data matching, on the basis of protected health information (PHI) common to both databases, to compare primary brain tumors from Veterans and non-Veterans diagnosed from 2000 to 2016. Working with this matched data set, we used six data elements that did not contain PHI, to assess the feasibility of using deterministic data matching to compare Veterans and non-Veterans.

resultsBetween 2000 and 2016, 223 Veterans from Ohio had a primary brain tumor; of those, 55 (25%) were not included in Ohio Cancer Incidence Surveillance System. Direct data matching showed that Veterans experienced a greater proportion of glioblastomas (41%) compared with non-Veterans (21%). Sex did not account for this difference. Deterministic data matching within the matched data set found that 75% (126 of 168) of Veterans had exact matches for at least five of six non-PHI variables common to both databases.

conclusionThis study indicated that direct and deterministic data matching approaches to compare brain tumors in Veterans and in non-Veterans is feasible. This approach has the potential to promote comparisons of the distribution of tumors, the impact of chemical and environmental exposures, treatment trajectories, and clinical outcomes among Veteran and non-Veteran populations with brain tumors as well as other cancers and rare diseases.

Indexed as

Brain NeoplasmsVeteransHumansIncidenceRegistriesUnited StatesUnited States Department of Veterans Affairs

Identifiers

PMID34554825
PMCPMC8807020
OpenAlexW3200550339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.