ArticleThe New England journal of medicine2021
Race, Genetic Ancestry, and Estimating Kidney Function in CKD.
Open access · greenAbstract readMulticenter Study
In one paragraph
Article in The New England journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 2 pooled it
24.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
121 citing papers in PubMed, 2 syntheses or guidelines pooled it, 215 citations in OpenAlex.
- Bias and Accuracy of Glomerular Filtration Rate Estimating Equations in the US: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- The prevalence of chronic kidney disease in South Africa - limitations of studies comparing prevalence with sub-Saharan Africa, Africa, and globally.BMC nephrology · 2023Pooled it
- The Effect of Periodontal Therapy on Renal Function and Diabetes Control in Patients With Chronic Kidney Disease. A Randomised Controlled Clinical Trial.Journal of clinical periodontology · 2026Trial
- Association of Three HIF-1α Genotypes With Susceptibility and Severity of Chronic Kidney Disease.Clinical and translational science · 2026Article
- Indices of obesity, malnutrition and inflammation are strong predictors of mortality in adults with type 2 diabetes: the FIELD study.Diabetologia · 2026Article
- Sex-Specific Associations of Monocyte-Based Inflammatory Indices with Renal Dysfunction and Hyperuricemia in the Saudi General Adult Population.Healthcare (Basel, Switzerland) · 2026Article
- Relationship between medication class and ambulatory blood pressure profile in the chronic renal insufficiency cohort (CRIC) study.Journal of human hypertension · 2026Article
- Evaluation of the association between magnesium depletion score and wound healing following the extraction of lower impacted third molars: a prospective observational cohort study.BMC oral health · 2026Observational
- Incorporating polygenic risk scores and social determinants of health across populations: Considerations and best practices in research.American journal of human genetics · 2026Review
- Integrating genetic ancestry into clinical care: Accuracy, utility, and stakeholder views.Journal of community genetics · 2026Article
- African ancestry-enriched variants in the GATM gene are associated with elevated serum creatinine levels.Genome medicine · 2026Article
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- Chronic Kidney Disease Severity and Risk of Cognitive Impairment.JAMA network open · 2026Article
- Renin-Angiotensin System Inhibitors in Patients With Nonproteinuric Chronic Kidney Disease and Kidney Outcomes: Findings From the CRIC Study.Kidney medicine · 2026Article
- Impact of Adopting the Race/Ethnicity-Free 2021 CKD-EPI Equation on Cardiovascular Risk Stratification in a Multiethnic European Population: Results from the HELIUS Study.Global heart · 2026Article
- Article
- Article
- Longitudinal evaluation of glomerular filtration rate across adolescence and early adulthood in youth with type 1 diabetes: associations with clinical and social risk factors.Frontiers in endocrinology · 2026Article
- Review
61 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
22 authors at 1 institution in 1 country.
Chi-Yuan HsuFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Wei YangFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Rishi V ParikhFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Amanda H AndersonFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Teresa K ChenFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Debbie L CohenFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Jiang HeFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Madhumita J MohantyFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
James P LashFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Katherine T MillsFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Anthony N MuiruFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Afshin ParsaFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Milda R SaundersFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Tariq ShafiFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Raymond R TownsendFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).ORCID 0000-0002-3215-9118
Sushrut S WaikarFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).ORCID 0000-0003-4004-326X
Jianqiao WangFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Myles WolfFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Thida C TanFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Harold I FeldmanFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
Alan S GoFrom the Division of Nephrology, Department of Medicine (C.H., A.N.M., A.S.G.), and the Departments of Epidemiology and Biostatistics (A.S.G.), University of California, San Francisco, San Francisco, the Division of Research, Kaiser Permanente Northern California, Oakland (C.H., R.V.P., T.C.T., A.S.G.), the Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena (A.S.G.), and the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto (A.S.G.) - all in California; the Department of Biostatistics, Epidemiology, and Informatics and the Center for Clinical Epidemiology and Biostatistics (W.Y., J.W., H.I.F.), the Division of Division of Renal-Electrolyte and Hypertension (D.L.C.), and the Department of Medicine (R.R.T.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (A.H.A., J.H., K.T.M.) and the Tulane University Translational Science Institute (A.H.A., J.H., K.T.M.), New Orleans; the Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, and the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore (T.K.C.), and the Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda (A.P.) - all in Maryland; the Division of Nephrology, Department of Internal Medicine, Wayne State University, Detroit (M.J.M.); the Division of Nephrology, Department of Medicine, University of Illinois at Chicago (J.P.L.), and the Section of General Internal Medicine, Department of Medicine, University of Chicago (M.R.S.) - both in Chicago; the Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson (T.S.); the Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston (S.S.W.); and the Division of Nephrology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.W.).
CRIC Study Investigators
Kaiser Permanente · US
Funding
UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2MScientific and Data Coordinating Center(SDCC) for the P*U01DK060990 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI FELDMAN, HAROLD I · 2001 to 2017
$50.1MClinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0MMichigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9MInstitutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9MTulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Ning Liu · 2016 to 2026
$25.3MContinuation of the Coordinating Center for the Chronic Renal Insufficiency Cohort (CRIC) StudyU24DK060990 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Amanda Hyre Anderson, Laura M Dember · 2018 to 2026
$21.5MZonulin Antibodies in Intestinal Permeabilitiy in IDDMM01RR016500 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI ONUKWUGHA, EBERECHUKWU · 2002 to 2009
$20.2MStudy of the Care and Outcomes of REnal InsufficiencyU01DK060902 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI GO, ALAN S · 2001 to 2025
$19.5MLimited Competition for the Continuation of the Chronic Renal Insufficiency CohorU01DK061021 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI RAHMAN, MAHBOOB · 2001 to 2025
$17.3MProspective Renal Insufficiency Cohort Evaluation:PRICEU01DK060984 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI COHEN, DEBBIE L · 2001 to 2025
$17.0MProspective Cohort Study of Chronic Renal InsufficiencyU01DK061028 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAO, PANDURANGA S · 2001 to 2025
$16.9MNCATS NIH HHS M01RR16500NCATS NIH HHS P20GM109036NCATS NIH HHS UL1RR024131NCATS NIH HHS UL1RR029879NCATS NIH HHS UL1 TR000003NCATS NIH HHS UL1TR000003NCATS NIH HHS UL1 TR000424NCATS NIH HHS UL1TR000424NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1TR000433NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1TR000439NCRR NIH HHS M01 RR016500NCRR NIH HHS UL1 RR024131NCRR NIH HHS UL1 RR029879NIDDK NIH HHS K23 DK119562NIDDK NIH HHS R01 DK119199NIDDK NIH HHS R01DK119199NIDDK NIH HHS R01 DK139225NIDDK NIH HHS R21 DK130018NIDDK NIH HHS U01 DK060902NIDDK NIH HHS U01DK060902NIDDK NIH HHS U01 DK060963NIDDK NIH HHS U01DK060963NIDDK NIH HHS U01 DK060980NIDDK NIH HHS U01DK060980NIDDK NIH HHS U01 DK060984NIDDK NIH HHS U01DK060984NIDDK NIH HHS U01 DK060990NIDDK NIH HHS U01DK060990NIDDK NIH HHS U01 DK061021NIDDK NIH HHS U01DK061021NIDDK NIH HHS U01 DK061022NIDDK NIH HHS U01DK061022NIDDK NIH HHS U01 DK061028NIDDK NIH HHS U01DK061028NIDDK NIH HHS U24 DK060990NIDDK NIH HHS U24DK060990NIGMS NIH HHS P20 GM109036
Abstract
backgroundThe inclusion of race in equations to estimate the glomerular filtration rate (GFR) has become controversial. Alternative equations that can be used to achieve similar accuracy without the use of race are needed.
methodsIn a large national study involving adults with chronic kidney disease, we conducted cross-sectional analyses of baseline data from 1248 participants for whom data, including the following, had been collected: race as reported by the participant, genetic ancestry markers, and the serum creatinine, serum cystatin C, and 24-hour urinary creatinine levels.
resultsUsing current formulations of GFR estimating equations, we found that in participants who identified as Black, a model that omitted race resulted in more underestimation of the GFR (median difference between measured and estimated GFR, 3.99 ml per minute per 1.73 m
conclusionsThe use of the serum creatinine level to estimate the GFR without race (or genetic ancestry) introduced systematic misclassification that could not be eliminated even when numerous non-GFR determinants of the serum creatinine level were accounted for. The estimation of GFR with the use of cystatin C generated similar results while eliminating the negative consequences of the current race-based approaches. (Funded by the National Institute of Diabetes and Digestive and Kidney Diseases and others.).
Indexed as
Glomerular Filtration RateRacial GroupsAdultAgedAlgorithmsBlack or African AmericanBlack PeopleCreatinineCross-Sectional StudiesCystatin CEthnicityFemaleHumansMaleMiddle AgedRenal Insufficiency, ChronicCreatinineCST3 protein, humanCystatin C
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