Evidence map›Paper›PMID 34554549›Full record

ReviewBiologia futura2021

Biologia Futura: the importance of 3D organoids-a new approach for research on neurological and rare diseases.

Tayfun Hilmi Akbaba, Can Ebru Bekircan-Kurt, Banu Balci-Peynircioglu, Burcu Balci-Hayta

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biologia futura, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tayfun Hilmi AkbabaDepartment of Medical Biology, Faculty of Medicine, Hacettepe University, Ankara, 06100, Turkey.ORCID http://orcid.org/0000-0002-3875-5244
Can Ebru Bekircan-KurtDepartment of Medical Biology, Faculty of Medicine, Hacettepe University, Ankara, 06100, Turkey.ORCID http://orcid.org/0000-0003-2355-6979
Banu Balci-PeynirciogluDepartment of Medical Biology, Faculty of Medicine, Hacettepe University, Ankara, 06100, Turkey.ORCID http://orcid.org/0000-0002-8627-8796
Burcu Balci-HaytaDepartment of Medical Biology, Faculty of Medicine, Hacettepe University, Ankara, 06100, Turkey. burcub@hacettepe.edu.tr.ORCID http://orcid.org/0000-0002-1780-2988
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3D cell cultures and organoid approach are increasingly being used for basic research and drug discovery of several diseases. Recent advances in these technologies, enabling research on tissue-like structures created in vitro is very important for the value of the data produced. Application of 3D cultures will not only contribute to advancing basic research, but also help to reduce animal usage in biomedical science. The 3D organoid approach is important for research on diseases where patient tissue is difficult to obtain. Therefore, this review aims to show recent advances in the 3D organoid technology in disease modeling and potential usage in translational and personalized medicine of diseases with limited patient material such as neurological diseases and rare diseases.

Indexed as

Cell Culture TechniquesForecastingHumansNervous System DiseasesOrganoidsRare Diseases3D organoids; disease modelingNeurological diseaseRare disease

Identifiers

PMID34554549
OpenAlexW3126628316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.