Evidence map›Paper›PMID 34554540›Full record

ArticleBiologia futura2019

Analysis of aristolochlic acids and evaluation of antibacterial activity of Aristolochia clematitis L.

Gergely Sámuel Bartha, Gergő Tóth, Péter Horváth, Eszter Kiss, Nóra Papp, Monika Kerényi

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Article in Biologia futura, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Plants (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Bioactive Compounds ofMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gergely Sámuel BarthaDepartment of Pharmacognosy, University of Pécs, Rókus u. 2, Pécs, H-7624, Hungary.
Gergő TóthDepartment of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre u. 9, Budapest, H-1092, Hungary.
Péter HorváthDepartment of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre u. 9, Budapest, H-1092, Hungary.
Eszter KissDepartment of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre u. 9, Budapest, H-1092, Hungary.
Nóra PappDepartment of Pharmacognosy, University of Pécs, Rókus u. 2, Pécs, H-7624, Hungary.
Monika KerényiDepartment of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti út 12, Pécs, H-7624, Hungary. kerenyi.monika@pte.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeveral Aristolochia species were used as medicinal herb across Europe and in recent years, their antimicrobial activity has also been investigated. MATERIALS AND

methodsIn this study, A. clematitis was selected to evaluate the aristolochic acids I and II (AA I and AA II) concentrations and the antimicrobial activity of methanol, hexane, butanol, and ethyl acetate extracts of the root, stem, leaf, root, and fruit. AA I and AA II contents were measured by a validated high-performance liquid chromatography-ultraviolet method.

resultsEach fraction of the plant contained AA I and AA II and the root was found to have the highest contents of AA I (1.09%) and AA II (0.7454%). The minimum inhibitory concentrations of all extracts were determined by standard microdilution method. The fruit's extracts showed the most efficient antimicrobial effect against both methicillin sensitive and resistant Staphylococcus aureus strains.

conclusionCorrelation between the AA I and AA II concentrations and the antimicrobial effect was not found.

Indexed as

antimicrobial effectAristolochia clematitisaristolochic acidHPLC

Identifiers

PMID34554540

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