Evidence map›Paper›PMID 34554531›Full record

ArticleBiologia futura2020

Differential epidemiology and antibiotic resistance of lactose-fermenting and non-fermenting Escherichia coli: Is it just a matter of taste?

Márió Gajdács, Marianna Ábrók, Andrea Lázár, Katalin Burián

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Biologia futura, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Whole-Genome Characterisation of ESBL-ProducingAntibiotics (Basel, Switzerland) · 2022
    Article
  4. Colistin Resistance and Molecular Characterization of the Genomes ofFrontiers in cellular and infection microbiology · 2022
    Article
  5. Characterization ofInfection and drug resistance · 2021
    Article
  6. Transmission Media of Foodborne Diseases as an Index Prediction of DiarrheagenicInternational journal of environmental research and public health · 2020
    Observational
  7. Article
  8. Article
  9. Resistance and Heteroresistance to Colistin inInfection and drug resistance · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Márió GajdácsDepartment of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Eötvös Utca 6., Szeged, 6720, Hungary. mariopharma92@gmail.com.ORCID http://orcid.org/0000-0003-1270-0365
Marianna ÁbrókInstitute of Clinical Microbiology, Faculty of Medicine, University of Szeged, Semmelweis utca 6., Szeged, 6725, Hungary.
Andrea LázárInstitute of Clinical Microbiology, Faculty of Medicine, University of Szeged, Semmelweis utca 6., Szeged, 6725, Hungary.
Katalin BuriánInstitute of Clinical Microbiology, Faculty of Medicine, University of Szeged, Semmelweis utca 6., Szeged, 6725, Hungary.
University of Szeged · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infections (UTIs) are some of the most common infections affecting humans worldwide. Occurrence of atypical, lactose non-fermenting, biochemically "inactive" strains of E. coli in clinical material has been described in the literature, which may cause a significant diagnostic challenge. The present retrospective microbiological study was carried out using isolates and data collected between January 1, 2013, and December 31, 2017, at the Institute of Clinical Microbiology. n = 24,285 positive urine samples were noted during the study period, out of which, samples positive for either lac + and lac- E. coli were included in the analysis. E. coli represented n = 7075 (55.8% ± 4.6%) of outpatient and n = 4916 (42.4% ± 3.6%) of inpatient isolates. n = 401 (3.3%; 80.2 ± 14.6/year) lac- E. coli isolates were identified from urinary tract infections. The ratio of lac- E. coli isolates was significantly higher in outpatient samples (262 vs. 139). Resistance levels of lac- isolates for antibiotics commonly used for treating UTIs were significantly higher for both inpatient and outpatient isolates: norfloxacin, ciprofloxacin, fosfomycin and nitrofurantoin. It is essential to pay attention to the presence of lac- strains, and their omission from clinical material during diagnostic procedures may have significant consequences for epidemiological studies and therapy.

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsEscherichia coliEscherichia coli InfectionsFermentationHumansLactoseRetrospective StudiesUrinary Tract InfectionsAnti-Bacterial AgentsLactoseAntibioticsBiochemical testingE. coliEpidemiologyLactose non-fermentingUrinary tract infections

Identifiers

PMID34554531
OpenAlexW3033737424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.