Evidence map›Paper›PMID 34554502›Full record

ReviewBiologia futura2021

Membrane nanotubes are ancient machinery for cell-to-cell communication and transport. Their interference with the immune system.

János Matkó, Eszter Angéla Tóth

Open access · hybridAbstract readReview
In one paragraph

Review in Biologia futura, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. ROS are evolutionary conserved cell-to-cell stress signals.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Cell-cell communication in African trypanosomes.Microbiology (Reading, England) · 2023
    Review
  5. Article
  6. Frontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

János MatkóDepartment of Immunology, Institute of Biology, Eötvös Loránd University, H-1117 Pázmány Péter sétány 1/C, Budapest, Hungary. matkojani52@gmail.com.
Eszter Angéla TóthATRC Aurigon Toxicological Research Center, H-2120 Pálya utca 2, Dunakeszi, Hungary.
Aurigon (Hungary) · HUEötvös Loránd University · HU

Funding

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal (HU) K104971
6 · The paper itself

Abstract

Nanotubular connections between mammalian cell types came into the focus only two decades ago, when "live cell super-resolution imaging" was introduced. Observations of these long-time overlooked structures led to understanding mechanisms of their growth/withdrawal and exploring some key genetic and signaling factors behind their formation. Unbelievable level of multiple supportive collaboration between tumor cells undergoing cytotoxic chemotherapy, cross-feeding" between independent bacterial strains or "cross-dressing" collaboration of immune cells promoting cellular immune response, all via nanotubes, have been explored recently. Key factors and "calling signals" determining the spatial directionality of their growth and their overall in vivo significance, however, still remained debated. Interestingly, prokaryotes, including even ancient archaebacteria, also seem to use such NT connections for intercellular communication. Herein, we will give a brief overview of current knowledge of membrane nanotubes and depict a simple model about their possible "historical role".

Indexed as

AnimalsBiological TransportCell CommunicationCell Membrane StructuresCells, CulturedHumansImmune SystemModels, BiologicalNanotubesProkaryotic Cells(Archae) BacteriaImmunomodulationIntercellular transportLong-distance signalingMembrane nanotubesNanoparticle therapy

Identifiers

PMID34554502
PMCPMC7869423
OpenAlexW3127023074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.