Evidence map›Paper›PMID 34554375›Full record

Observational studySleep & breathing = Schlaf & Atmung2022

A novel, simple, and accurate pulse oximetry indicator for screening adult obstructive sleep apnea.

Carlos Alberto Nigro, Gonzalo Castaño, Ignacio Bledel, Alfredo Colombi, María Cecilia Zicari

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Observational
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlos Alberto NigroHead of Pneumonology, Hospital Alemán, Pueyrredón 1640, CP 1418, Ciudad Autónoma de Buenos Aires, Argentina. cnigro@intramed.net.ORCID 0000-0001-9011-3428
Gonzalo CastañoHead of Pneumonology, Hospital Alemán, Pueyrredón 1640, CP 1418, Ciudad Autónoma de Buenos Aires, Argentina.
Ignacio BledelHead of Pneumonology, Hospital Alemán, Pueyrredón 1640, CP 1418, Ciudad Autónoma de Buenos Aires, Argentina.
Alfredo ColombiAkonic SA, Av. Gral. Mosconi 2886, 1419, Buenos Aires, Argentina.
María Cecilia ZicariAkonic SA, Av. Gral. Mosconi 2886, 1419, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of the study was to develop a multiparametric oximetry indicator (IMp-SpO2) to diagnose obstructive sleep apnea in adults. MATERIAL AND

methodThis was an observational, retrospective study of diagnostic accuracy. We included adults who had had a diagnostic polysomnography with few artifacts and a total sleep time of at least 180 min in the sleep laboratory. Obstructive sleep apnea (OSA) was defined as an apnea-hypopnea index (AHI) ≥ 5. The database was randomly divided into an experimental (Exp-G) and validation (Val-G) group. The program calculated several parameters of oxygen saturation variability (Par-VarSpO2): (a) oxygen desaturation index (ODI ≥ 3, 4%) and (b) 90, 95, and 97.5 percentiles of both the number of oxygen desaturations ≥ 3 and 4% (P90-97.5 OD3/4 W5-60) and SpO2 standard deviations in moving windows from 5 to 60 min (P90-P97.5 SDSpO2 W5-10). Area under the ROC curve (AUC-ROC), sensitivity, specificity, positive/negative likelihood ratios, and accuracy were calculated.

resultsOf 1141 adults included in the study, experimental (571) and validation group (570) were similar (women 47% vs 45%, BMI 27.5 kg/m

conclusionThe IMp-SpO2 showed a > 90% accuracy for OSA diagnosis in adults.

Indexed as

Sleep Apnea, ObstructiveAdultFemaleHumansOximetryOxygenRetrospective StudiesOxygenMachine learningObstructive sleep apnea syndromeOximetryPattern recognitionScreeningSignal processing

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.