Evidence map›Paper›PMID 34554367›Full record

ArticleThe international journal of cardiovascular imaging2021

INtra-procedural ultraSound Imaging for DEtermination of atrial wall thickness and acute tissue changes after isolation of the pulmonary veins with radiofrequency, cryoballoon or laser balloon energy: the INSIDE PVs study.

Milena Leo, Giovanni Luigi De Maria, Andre Briosa E Gala, Michael Pope, Abhirup Banerjee, Andrew Kelion, Michala Pedersen, Kim Rajappan, Matthew Ginks, Yaver Bashir and 2 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05781282 (Pulmonary Vein Imaging by ICE After Atrial Fibrillation Ablation to Predict Recurrences), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05781282 phase4unknown statusnot on this map

Pulmonary Vein Imaging by ICE After Atrial Fibrillation Ablation to Predict Recurrences

TypeinterventionalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2021 to 2024Enrolled18ConditionsAtrial Fibrillation RecurrentArmsAtrial fibrillation ablation
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Left atrial wall thickness; at the forefront of atrial fibrillation ablation strategies.The international journal of cardiovascular imaging · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Milena LeoOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK. milena.leo@ouh.nhs.uk.ORCID http://orcid.org/0000-0001-6991-6664
Giovanni Luigi De MariaOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK.
Andre Briosa E GalaOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK.
Michael PopeOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK.
Abhirup BanerjeeDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Andrew KelionOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK.
Michala PedersenOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK.
Kim RajappanOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK.
Matthew GinksOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK.
Yaver BashirOxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 7BA, UK.
Ross J HunterBarts Heart Centre, London, UK.
Tim BettsOxford NIHR Biomedical Research Centre, Oxford, UK.
Oxford University Hospitals NHS Trust · GBBritish Heart Foundation · GBOxford BioMedica (United Kingdom) · GBOxford Health NHS Foundation Trust · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preliminary data in human suggest that both Intracardiac echocardiography (ICE) and Intravascular ultrasound (IVUS) can be used for real-time information on the left atrial (LA) wall thickness and on the acute tissue changes produced by energy delivery. This pilot study was conducted to compare ICE and IVUS for real-time LA wall imaging and assessment of acute tissue changes produced by radiofrequency (RF), cryo and laser catheter ablation. Patients scheduled for RF, cryoballoon or laser balloon Pulmonary Vein Isolation (PVI) catheter ablation were enrolled. Each pulmonary vein (PV) was imaged before and immediately after ablation with either ICE or IVUS. The performance of ICE and IVUS for imaging were compared. Pre- and post-ablation measurements (lumen and vessel diameters, areas and sphericity indexes, wall thickness and muscular sleeve thickness) were taken at the level of each PV ostium. A total of 48 PVs in 12 patients were imaged before and after ablation. Both ICE and IVUS showed acute tissue changes. Compared to IVUS, ICE showed higher imaging quality and inter-observer reproducibility of the PV measurements obtained. Acute wall thickening suggestive of oedema was observed after RF treatment (p = 0.003) and laser treatment (p = 0.003) but not after cryoablation (p = 0.69). Our pilot study suggests that ICE might be preferable to IVUS for LA wall thickness imaging at the LA-PV junctions during ablation. Ablation causes acute wall thickening when using RF or laser energy, but not cryoenergy delivery. Larger studies are needed to confirm these preliminary findings.

Indexed as

Atrial FibrillationCatheter AblationPulmonary VeinsEchocardiographyHumansLasersPilot ProjectsPredictive Value of TestsReproducibility of ResultsTreatment OutcomeUltrasonographyAcute wall changes after ablationCryoenergyIntracardiac echocardiographyIntravascular ultrasoundLaser energyLeft atrial wall thicknessRadiofrequency energy

Identifiers

PMID34554367
OpenAlexW3175812929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.