ArticleGeneral thoracic and cardiovascular surgery2022
Impact of preoperative comorbidities on postoperative complication rate and outcome in surgically resected non-small cell lung cancer patients.
Article in General thoracic and cardiovascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 32 citations in OpenAlex.
- Comments and suggestions on the article "the effects of preoperative anaemia on postoperative complications in patients undergoing thoracic surgery".Turkish journal of surgery · 2026Article
- Uniportal-VATS for Early-Stage NSCLC in Octogenarians: A Single-Center, Retrospective Study of Surgical and Short-Term Oncological Outcomes.Journal of personalized medicine · 2026Article
- Association between diaphragm thickness and postoperative complications in elderly patients with non-small-cell lung cancer.Surgery today · 2026Article
- Stage I non-small cell lung cancer: improving patient selection for minimally invasive lobectomy or stereotactic ablative radiotherapy based on clinical characteristics.British journal of cancer · 2026Article
- Development and internal validation of a multivariable nomogram for predicting postoperative complications and prolonged length of hospital stay in patients undergoing video-assisted thoracoscopic surgery: a single-center prospective cohort study.Frontiers in medicine · 2026Article
- A New Era, New Risks: The Cardio-Oncology Perspective on Immunotherapy in Non-Small Cell Lung Cancer.Cancers · 2025Review
- Postoperative arrhythmias in geriatric lung cancer patients undergoing thoracoscopic surgery: an exploration of prevalence and influencing factors.Perioperative medicine (London, England) · 2025Article
- Intersection of Race, Rurality, and Income in Defining Access to Minimally Invasive Lung Surgery.The Annals of thoracic surgery · 2025Article
- Performing High-Quality Sublobar Resections: Key Differences Between Wedge Resection and Segmentectomy.Cancers · 2024Review
- Analysis of risk factors of postoperative complication for non-small cell lung cancer.BMC pulmonary medicine · 2024Article
- Perioperative Challenges: Analysis of Surgical Complications in Screening Lung Carcinoma Patient.Cureus · 2024Article
- Magnitude and associated factors of postoperative mortality among patients who underwent surgery in Ethiopia: systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Review
- Article
- Review
- Evaluating the Impact of Race-Neutral Interpretation of Preoperative Pulmonary Function.Annals of the American Thoracic Society · 2024Article
- Predictors associated with Clavien-Dindo complications in lung cancer surgery: A retrospective cohort study.PloS one · 2024Article
- "Low-age, low-frequency" lung cancer screening strategies maybe adaptable to the situation in China.BMC surgery · 2023Article
- Seven preoperative factors have strong predictive value for postoperative pneumonia in patients undergoing thoracoscopic lung cancer surgery.Translational lung cancer research · 2023Article
- Article
- Are Extensive Open Lung Resections for Elderly Patients with Lung Cancer Justified?Current oncology (Toronto, Ont.) · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to analyze whether comorbidities impact postoperative complication rate or survival after anatomical lung resection for non-small cell lung cancer (NSCLC).
methodsA retrospective analysis of 1219 patients who underwent NSCLC resection between 2000 and 2015 was performed. Analyzed comorbidities included chronic obstructive lung disease (COPD), hypertension, coronary artery disease (CAD), peripheral artery disease, myocardial infarction history, diabetes mellitus, renal insufficiency and other malignancies.
resultsMost patients (78.9%) had comorbidities, most commonly hypertension (34.1%) followed by COPD (26.4%) and other malignancies (19%). The overall complication rate was 38.6% (26.4% pulmonary; 14.8% cardiac; and 3.0% gastrointestinal). Hypertension (odds ratio (OR) = 1.492, p = 0.031) was associated with more cardiac complications. Heavy smoking (OR = 1.008, p = 0.003) and low body mass index (BMI) (OR = 0.932, p < 0.001) affected the pulmonary complication rate significantly. None of the included comorbidities affected the overall complication rate or the survival negatively. However, the patient characteristics of advanced age (p < 0.001), low BMI (p = 0.008), and low FEV1 (p = 0.008) affected the overall complication rate as well as survival (each p < 0.001).
conclusionAdvanced age, low BMI, and low FEV1 were predictive of greater complication risk and shorter long-term survival in patients who underwent NSCLC resection. Cardiac complications were associated with hypertension and CAD, whereas pulmonary complications were associated with a high pack year count.
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