Evidence map›Paper›PMID 34554260›Full record

ArticleSchizophrenia bulletin2022

Unstable Belief Formation and Slowed Decision-making: Evidence That the Jumping-to-Conclusions Bias in Schizophrenia Is Not Linked to Impulsive Decision-making.

Wolfgang Strube, Camelia Lucia Cimpianu, Miriam Ulbrich, Ömer Faruk Öztürk, Thomas Schneider-Axmann, Peter Falkai, Louise Marshall, Sven Bestmann, Alkomiet Hasan

Open access · bronzeAbstract read
In one paragraph

Article in Schizophrenia bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Action prediction in psychosis.Schizophrenia (Heidelberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Wolfgang StrubeDepartment of Psychiatry and Psychotherapy, Ludwig Maximillian University, Munich,Germany.
Camelia Lucia CimpianuDepartment of Psychiatry and Psychotherapy, Ludwig Maximillian University, Munich,Germany.
Miriam UlbrichDepartment of Psychiatry and Psychotherapy, Ludwig Maximillian University, Munich,Germany.
Ömer Faruk ÖztürkDepartment of Psychiatry and Psychotherapy, Ludwig Maximillian University, Munich,Germany.ORCID 0000-0003-3665-0526
Thomas Schneider-AxmannDepartment of Psychiatry and Psychotherapy, Ludwig Maximillian University, Munich,Germany.
Peter FalkaiDepartment of Psychiatry and Psychotherapy, Ludwig Maximillian University, Munich,Germany.
Louise MarshallDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London, UK.
Sven BestmannDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London, UK.
Alkomiet HasanDepartment of Psychiatry, Psychotherapy and Psychosomatics of the University Augsburg, Medical Faculty, University of Augsburg, Bezirkskrankenhaus Augsburg, Augsburg, Germany.
University of Augsburg · DEMax Planck Institute of Psychiatry · DENational Hospital for Neurology and Neurosurgery · GBWellcome Centre for Human Neuroimaging · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundJumping-to-conclusions (JTC) is a prominent reasoning bias in schizophrenia (SCZ). While it has been linked to not only psychopathological abnormalities (delusions and impulsive decision-making) but also unstable belief formation, its origin remains unclear. We here directly test to which extend JTC is associated with delusional ideation, impulsive decision-making, and unstable belief formation.

methodsIn total, 45 SCZ patients were compared with matched samples of 45 patients with major depressive disorder (MDD) and 45 healthy controls (HC) as delusions and JTC also occur in other mental disorders and the general population. Participants performed a probabilistic beads task. To test the association of JTC with measures of delusions (Positive and Negative Syndrome Scale [PANSS]positive, PANSSpositive-factor, and Peter Delusions Inventory [PDI]), Bayesian linear regressions were computed. For the link between JTC and impulsive decision-making and unstable beliefs, we conducted between-group comparisons of "draws to decision" (DTD), "decision times" (DT), and "disconfirmatory evidence scores" (DES).

resultsBayesian regression obtained no robust relationship between PDI and DTD (all |R2adj| ≤ .057, all P ≥ .022, all Bayes Factors [BF01] ≤ 0.046; α adj = .00833). Compared with MDD and HC, patients with SCZ needed more time to decide (significantly higher DT in ambiguous trials: all P ≤ .005, r2 ≥ .216; numerically higher DT in other trials). Further, SCZ had unstable beliefs about the correct source jar whenever unexpected changes in bead sequences (disconfirmatory evidence) occurred (compared with MDD: all P ≤ .004 and all r2 ≥ .232; compared with HC: numerically higher DES). No significant correlation was observed between DT and DTD (all P ≥ .050).

conclusionsOur findings point toward a relationship of JTC with unstable belief formation and do not support the assumption that JTC is associated with impulsive decision-making.

Indexed as

CultureDecision MakingAdultAnalysis of VarianceChi-Square DistributionFemaleGermanyHumansImpulsive BehaviorMaleMiddle AgedProblem SolvingSchizophreniabeads taskjumping-to-conclusions (JTC) biasprobabilistic reasoningschizophreniaslowed decision-makingunstable belief-formation

Identifiers

PMID34554260
PMCPMC8886605
OpenAlexW3201034638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.