ArticleJMIR mental health2021
Virtual Reality for Supporting the Treatment of Depression and Anxiety: Scoping Review.
Article in JMIR mental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07081425 (The Effect of Virtual Reality Intervention on Pain and Anxiety During Drain Removal), which is not on this map. Cited by 59 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Virtual Reality Intervention on Pain and Anxiety During Drain Removal: Randomized Controlled Study
Who cites it
59 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- The effect of virtual reality technology on the intervention of mental health problems among healthcare workers: a systematic review.Frontiers in public health · 2026Pooled it
- Using Virtual Reality to Improve Outcomes Related to Quality of Life Among Older Adults With Serious Illnesses: Systematic Review of Randomized Controlled Trials.Journal of medical Internet research · 2025Pooled it
- The effectiveness of virtual reality in enhancing mindfulness: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Revealing the impact of teaching methods on anxiety among college students through a bibliometric study.Frontiers in psychology · 2025Pooled it
- Does virtual reality reduce anxiety and pain in patients undergoing third molar surgery? A systematic review and meta-analysis.Oral and maxillofacial surgery · 2024Pooled it
- Evaluating virtual reality technology in psychotherapy: impacts on anxiety, depression, and ADHD.Frontiers in psychiatry · 2024Pooled it
- Assessing Patient Adherence to and Engagement With Digital Interventions for Depression in Clinical Trials: Systematic Literature Review.Journal of medical Internet research · 2023Pooled it
- Effect of web-implemented exercise interventions on depression and anxiety in patients with neurological disorders: a systematic review and meta-analysis.Frontiers in neurology · 2023Pooled it
- Multisensory virtual reality reduces postoperative delirium in elderly patients undergoing laparoscopic gastrointestinal surgery: A single-centre randomised controlled trial.European journal of anaesthesiology · 2026Trial
- Trial
- Examining the Efficacy of Extended Reality-Enhanced Behavioral Activation for Adults With Major Depressive Disorder: Randomized Controlled Trial.JMIR mental health · 2024Trial
- Curiosity in a Novel Virtual Reality Scenario and Its Association With Symptoms of Depression: Observational Pilot Investigation.JMIR formative research · 2026Observational
- A systematic review on mindfulness-based immersive interventions in depressive disorders.Npj mental health research · 2026Review
- Practitioner Acceptability of Virtual Reality Therapy in Mental Health Care: Evidence From Greece.Brain and behavior · 2026Article
- Anshen Jieyu Decoction: A Promising Remedy for Depression via AKT/mTOR Pathway Modulation in CUMS Rats.Brain and behavior · 2026Article
- Advances in ocular motor and pupil biomarkers for neurological disorders.Brain communications · 2026Review
- Effectiveness of virtual reality-based intervention for adolescent depressive disorder: a randomized controlled trial protocol.Frontiers in psychology · 2026Article
- Evaluating the Effects of Clinician Prescribing and Implementation Materials on Adoption of Virtual Reality Therapeutics: Randomized Feasibility Pilot Study.JMIR XR and spatial computing · 2026Article
- Assessing Patient Acceptance of Being Offered a Virtual Calm Room in Psychiatric Inpatient Care: Mixed Methods Study.JMIR formative research · 2025Article
- Virtual reality therapy for adolescent depression: a prospective observational study.BMC psychiatry · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMental health conditions pose a major challenge to health care providers and society at large. The World Health Organization predicts that by 2030, mental health conditions will be the leading cause of disease burden worldwide. The current need for mental health care is overwhelming. In New Zealand, 1 in 6 adults has been diagnosed with common mental disorders, such as depression and anxiety disorders, according to a national survey. Cognitive behavioral therapy (CBT) has been shown to effectively help patients overcome a wide variety of mental health conditions. Virtual reality exposure therapy (VRET) might be one of the most exciting technologies emerging in the clinical setting for the treatment of anxiety and depression.
objectiveThis study aims to investigate the virtual reality (VR) technologies currently being used to help support the treatment of depression and anxiety. We also aim to investigate whether and how CBT is included as part of VRET and look at the VR technologies and interventions that have been used in recent studies on depression and anxiety.
methodsWe performed a scoping review. To identify significant studies, we decided to use already aggregated sources from the Google Scholar database. Overall, the goal of our search strategy was to limit the number of initial results related to VR in mental health to only a relevant minimum.
resultsUsing our defined keywords, Google Scholar identified >17,300 articles. After applying all the inclusion and exclusion criteria, we identified a total of 369 articles for further processing. After manual evaluation, 34 articles were shortlisted; of the 34 articles, 9 (26%) reported the use of CBT with VR. All of the articles were published between 2017 and 2021. Out of the 9 studies, CBT was conducted within a VR environment in 5 (56%) studies, whereas in the remaining 4 (44%) studies, CBT was used as an addition to VRET. All 9 studies reported the use of CBT either in vivo or in a virtual environment to be effective in supporting the treatment of anxiety or depression.
conclusionsMost studies demonstrated the use of VR to be effective for supporting the treatment of anxiety or depression in a range of settings and recommended its potential as a tool for use in a clinical environment. Even though standalone headsets are much easier to work with and more suitable for home use, the shift from tethered VR headsets to standalone headsets in the mental health environment was not observed. All studies that looked at the use of CBT either in vivo or in a virtual environment found it to be effective in supporting the treatment of anxiety or depression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.