ArticleJournal of rehabilitation medicine2021
Within-subject variation in the cognitive timed up and go test as an explanatory variable in fall risk in patients with parkinson's disease.
Article in Journal of rehabilitation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Instrumental balance assessment in Parkinson's disease and parkinsonism. A systematic review with critical appraisal of clinical applications and quality of reporting.Frontiers in neurology · 2025Pooled it
- Instrumented Timed Up and Go Analysis Identifies Biomechanical Markers Across Early Hoehn and Yahr Stages of Parkinson's Disease.Sensors (Basel, Switzerland) · 2026Article
- Relationship of foot pain with the increased risk of falls in patients with Parkinson's disease.Journal of foot and ankle research · 2024Article
- Improvements in clinical signs and symptoms of Parkinson's disease using photobiomodulation: a five-year follow-up.BMC neurology · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the use of within-subject variation in the Cognitive Timed Up and Go test (Cognitive TUGWSV) as an explanatory variable in fall risk in the Parkinson's disease population.
designCross-sectional study.
methodsFifty-three patients with Parkinson's disease completed 3 trials of the Cognitive TUGWSV. Within-subject variation was calculated using the standard deviation of an individual's repeated measurements, and compared on the basis of the fall history reported in the previous 6 months. Participants who reported < 2 falls were classified as "non-recurrent fallers" (n = 31) and those who reported ≥ 2 falls were classified as "recurrent fallers" (n = 22). Univariate and a multivariate logistic regression were used to investigate the statistical impact of the Cognitive TUGWSV as an explanatory variable in fall risk. Discriminative ability and cut-off score were determined based on receiver operating characteristic analysis.
resultsThere was a significant difference between groups in the Cognitive TUGWSV (p = 0.002). Univariate logistic regression indicated a significant association between Cognitive TUGWSV and fall risk (χ2=12.365, p < 0.001), with an odds ratio of 2.5 (95% confidence interval (95% CI) = 1.34-4.65). Multivariate logistic regression showed that body mass index (BMI), Falls Efficacy Scale-International (FES-I), Cognitive TUGWSV, and the mean velocity of the centre of foot pressure under closed eyes condition (Velocity COP (CE)) were significant explanatory variables in fall risk. Cognitive TUGWSV was the most important independent variable. Receiver operating characteristic analysis revealed an acceptable discriminative power (area under the curve (AUC) = 0.757, 95% CI = 0.619-0.864, p < 0.001) and a cut-off point of 1.53 s.
conclusionA higher Cognitive TUGWSV correlated significantly with higher fall risk. Thus, diagnostic tests and exercise programmes could consider Cognitive TUGWSV when assessing fall risk in the Parkinson's disease population.
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