Evidence map›Paper›PMID 34553104›Full record

ArticleHardwareX2021

Comparison of Design Approaches for Low-Cost Sampling Mechanisms in Open-Source Chemical Instrumentation.

Greggory Murray, Samuel Bednarski, Michael Hall, Samuel W Foster, SiJun Jin, Joshua J Davis, Wei Xue, Eric Constans, James P Grinias

Abstract read
In one paragraph

Article in HardwareX, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Greggory MurrayDepartment of Mechanical Engineering, Rowan University, Glassboro, NJ.
Samuel BednarskiDepartment of Mechanical Engineering, Rose-Hulman Institute of Technology, Terre Haute, IN.
Michael HallDepartment of Mechanical Engineering, Rose-Hulman Institute of Technology, Terre Haute, IN.
Samuel W FosterDepartment of Chemistry & Biochemistry, Rowan University, Glassboro, NJ.
SiJun JinDepartment of Mechanical Engineering, Rose-Hulman Institute of Technology, Terre Haute, IN.
Joshua J DavisDepartment of Chemistry & Biochemistry, Rowan University, Glassboro, NJ.
Wei XueDepartment of Mechanical Engineering, Rowan University, Glassboro, NJ.
Eric ConstansDepartment of Mechanical Engineering, Rose-Hulman Institute of Technology, Terre Haute, IN.
James P GriniasDepartment of Chemistry & Biochemistry, Rowan University, Glassboro, NJ.

Funding

Portable Liquid Chromatography Platform for Diverse Pharmaceutical ApplicationsR44GM137649 · NIGMS · AXCEND, LLC · PI LEE, MILTON L. · 2020 to 2022
$1.7M
NIGMS NIH HHS R44 GM137649
6 · The paper itself

Abstract

Robotic positioning systems are used in a variety of chemical instruments, primarily for liquid handling purposes, such as autosamplers from vials or well plates. Here, two approaches to the design of open-source autosampler positioning systems for use with 96-well plates are described and compared. The first system, a 3-axis design similar to many low-cost 3D printers that are available on the market, is constructed using an aluminum design and stepper motors. The other system relies upon a series of 3D printed parts to achieve movement with a series of linker arms based on Selective Compliance Assembly Robot Arm (SCARA) design principles. Full printer design files, assembly instructions, software, and user directions are included for both samplers. The positioning precision of the 3-axis system is better than the SCARA mechanism due to finer motor control, albeit with a slightly higher cost of materials. Based on the improved precision of this approach, the 3-axis autosampler system was used to demonstrate the generation of a segmented flow droplet stream from adjacent wells within a 96-well plate.

Indexed as

AutosamplerChemical AnalysisDroplet MicrofluidicsRobotics

Identifiers

PMID34553104
PMCPMC8452234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.