ArticleChem2021
A molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer.
Article in Chem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Hydrogen Bonding within DynamicJournal of the American Chemical Society · 2026Article
- Anion-Dependent Hydrogen-Bond Polarity Switching in Ethylene-bridged Urea Oligomers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- Chemically Fueled Communication Along a Scaffolded Nanoscale Array of Squaramides.Angewandte Chemie (International ed. in English) · 2023Article
- Dynamic and Persistent Cyclochirality in Hydrogen-Bonded Derivatives of Medium-Ring Triamines.Journal of the American Chemical Society · 2023Article
- Conformational preference in difluoroacetamide oligomers: probing the potential for foldamers with C-H⋯O hydrogen bonds.Organic & biomolecular chemistry · 2023Article
- Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer.Nature communications · 2023Article
- Screw sense and screw sensibility: communicating information by conformational switching in helical oligomers.Chemical Society reviews · 2023Review
- A ChiralJournal of the American Chemical Society · 2022Article
- Supramolecular interactions between ethylene-bridged oligoureas: nanorings and chains formed by cooperative positive allostery.Chemical science · 2022Article
- Dissecting Solvent Effects on Hydrogen Bonding.Angewandte Chemie (International ed. in English) · 2022Article
- Reversible Capture and Release of a Ligand Mediated by a Long-Range Relayed Polarity Switch in a Urea Oligomer.Journal of the American Chemical Society · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Communication of information through the global switching of conformation in synthetic molecules has hitherto entailed the inversion of chirality. Here, we report a class of oligomer through which information may be communicated through a global reversal of polarity. Ethylene-bridged oligoureas are constitutionally symmetrical, conformationally flexible molecules organized by a single chain of hydrogen bonds running the full length of the oligomer. NMR reveals that this hydrogen-bonded chain may undergo a coherent reversal of directionality. The directional uniformity of the hydrogen-bond chain allows it to act as a channel for the spatial communication of information on a molecular scale. A binding site at the terminus of an oligomer detects local information about changes in pH or anion concentration and transmits that information-in the form of a directionality switch in the hydrogen-bond chain-to a remote polarity-sensitive fluorophore. This propagation of polarity-encoded information provides a new mechanism for molecular communication.
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Registered trials
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