Evidence map›Paper›PMID 34552996›Full record

ArticleOpen forum infectious diseases2021

The Association of Human Leukocyte Antigen and COVID-19 in Southern China.

Xueping Yu, Kuoting Ho, Zhongliang Shen, Xiaoying Fu, Hongbo Huang, Delun Wu, Yancheng Lin, Yijian Lin, Wenhuang Chen, Milong Su and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xueping YuDepartment of Infectious Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Kuoting HoHI. Q Biomedical Laboratory, Quanzhou, Fujian, China.
Zhongliang ShenDepartment of Infectious Disease, Huashan Hospital, Fudan University, Shanghai, China.
Xiaoying FuHI. Q Biomedical Laboratory, Quanzhou, Fujian, China.
Hongbo HuangDepartment of Respiratory Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Delun WuHI. Q Biomedical Laboratory, Quanzhou, Fujian, China.
Yancheng LinHI. Q Biomedical Laboratory, Quanzhou, Fujian, China.
Yijian LinDepartment of Respiratory Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Wenhuang ChenDepartment of Infectious Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Milong SuDepartment of Clinical Laboratory, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Chao QiuDepartment of Infectious Disease, Huashan Hospital, Fudan University, Shanghai, China.
Xibin ZhuangDepartment of Respiratory Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Zhijun SuDepartment of Infectious Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human leukocyte antigen (HLA) polymorphism is hypothesized to be associated with diverse immune responses toward infectious diseases. Herein, by comparing against multiple subpopulation groups as control, we confirmed that HLA-B*15:27 and HLA-DRB1*04:06 were associated with coronavirus disease 2019 susceptibility in China. Both alleles were predicted to have weak binding affinities toward viral proteins.

Indexed as

COVID-19HLApopulation stratificationSARS-CoV-2susceptibility

Identifiers

PMID34552996
PMCPMC8436377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.