Evidence map›Paper›PMID 34552986›Full record

ArticleBioMed research international2021

Topical Delivery of Geranium/Calendula Essential Oil-Entrapped Ethanolic Lipid Vesicular Cream to Combat Skin Aging.

Alka Lohani, Anurag Verma, G Hema, Kamla Pathak

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Skin Aging: Insights into the Role of Fatty Acids.Current pharmaceutical design · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alka LohaniSchool of Pharmaceutical Sciences, IFTM University, 244102, Moradabad, India.ORCID https://orcid.org/0000-0003-2580-7524
Anurag VermaSchool of Pharmaceutical Sciences, IFTM University, 244102, Moradabad, India.ORCID https://orcid.org/0000-0003-3716-3033
G HemaDepartment of Biotechnology, Maharani's Science College for Women, 560001, Bangalore, India.
Kamla PathakPharmacy College Saifai, Uttar Pradesh University of Medical Sciences, 206130, Uttar Pradesh, India.ORCID https://orcid.org/0000-0001-9074-9792
Adesh University · INIFTM University · INTeerthanker Mahaveer University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study deals with the evaluation of the age-defying potential of topical cream formulations bearing Geranium essential oil/Calendula essential oil-entrapped ethanolic lipid vesicles (ELVs). Two types of cream formulations were prepared, viz., conventional and ELVs spiked o/w creams. Essential oil- (EO-) loaded ELVs were characterized by vesicle size, polydispersity index, encapsulation efficiency, and scanning electron microscopy. The cream formulations were evaluated for homogeneity, spreadability, viscosity, pH,

Indexed as

Drug Delivery SystemsAdministration, CutaneousAnimalsAntioxidantsBiphenyl CompoundsCalendulaCollagenasesDrug CompoundingEnzyme InhibitorsEthanolFemaleFree Radical ScavengersGeraniumHydrogen-Ion ConcentrationLipidsMale1,1-diphenyl-2-picrylhydrazylAntioxidantsBiphenyl CompoundsCollagenasesEnzyme InhibitorsEthanolFree Radical ScavengersLipidsNitric OxideOils, VolatilePancreatic ElastasePicratesSunscreening Agents

Identifiers

PMID34552986
PMCPMC8452390
OpenAlexW3199450384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.