ArticleFrontiers in veterinary science2021
Persistent Purine Metabolic Abnormality Induces the Aggravation of Visceral Inflammation and Intestinal Microbiota Dysbiosis in Magang Goose.
Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Hydroxypropyl starch enhances gut health in geese.Poultry science · 2026Article
- Effects of hydroxypropyl starch on intestinal health and transcriptome of geese.Scientific reports · 2025Article
- Effects of dietary protein sources and levels on uric acid metabolism, renal function, and inflammatory responses in goslings.Frontiers in veterinary science · 2025Article
- Effects and potential pathways of goose astrovirus infection on gosling hepatic lipid metabolism.Frontiers in microbiology · 2025Article
- Effects of stocking density on the homeostasis of uric acid and related liver and kidney functions in ducks.Animal bioscience · 2024Article
- Article
- Infection and innate immune mechanism of goose astrovirus.Frontiers in microbiology · 2023Review
- Feeding whole-plant ensiled corn stover affects growth performance, blood parameters, and Cecal microbiota of Holdobagy goose.Frontiers in veterinary science · 2023Article
- Effects of β-Carotin and Green Tea Powder Diets on Alleviating the Symptoms of Gouty Arthritis and Improving Gut Microbiota in C57BL/6 Mice.Frontiers in microbiology · 2022Article
- Gut microbiota remodeling: A promising therapeutic strategy to confront hyperuricemia and gout.Frontiers in cellular and infection microbiology · 2022Review
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Authors and funding
19 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gout is a disease involving abnormal purine metabolism that is widespread in mammals and birds. Goose is especially susceptible for gout in early stage. However, a few studies investigated the ontogenetic pattern of goslings with purine metabolic abnormality. Our studies were conducted to investigate whether persistent purine metabolic abnormality would lead to aggravation of visceral inflammation and intestinal microbiota dysbiosis in goose. A total of 132 1-day-old Magang geese were randomly divided into six replicates and fed a high-calcium and protein meal-based diet from 1 to 28 days. The experiment lasted for 28 days. Liver and kidney damages were observed in 14- and 28-day-old Magang geese, and liver inflammation increased with increasing age. In 28-day-old Magang geese, serum CAT and liver GSH-Px activity were significantly reduced. Furthermore, jejunum intestinal barrier was impaired and the abundance of
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