Antiviral Effectivity of Favipiravir Against Peste Des Petits Ruminants Virus Is Mediated by the JAK/STAT and PI3K/AKT Pathways.

Weifeng Zhang, Hualong Deng, Yanfen Liu, Shaohong Chen, You Liu, Yuntao Zhao

Open access · goldAbstract read

In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

0.5field-weighted citation impact, top 39% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

Ginsenoside Rh1 suppresses Peste des petits ruminants virus replication by inhibiting autophagy to promote interferon responses and restrict inflammatory responses.Frontiers in veterinary science · 2026
Article
The Nucleoside Analog GS-441524 Effectively Attenuates the In Vitro Replication of Multiple Lineages of Circulating Canine Distemper Viruses Isolated from Wild North American Carnivores.Viruses · 2025
Article
Proteomic and phosphoproteomic profilings reveal distinct cellular responses duringPeerJ · 2025
Article
Peste des petits ruminants virus infection induces endoplasmic reticulum stress and apoptosis via IRE1-XBP1 and IRE1-JNK signaling pathways.Journal of veterinary science · 2024
Article
Fuzhengjiedu San inhibits porcine reproductive and respiratory syndrome virus by activating the PI3K/AKT pathway.PloS one · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weifeng ZhangDepartment of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, China.

Hualong DengDepartment of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, China.

Yanfen LiuDepartment of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, China.

Shaohong ChenDepartment of Bioengineering, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, China.

You LiuDepartment of Bioengineering, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, China.

Yuntao ZhaoDepartment of Bioengineering, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, China.

Guangdong Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peste des petits ruminants virus (PPRV), belonging to the genus

Indexed as

antiviral activityfavipiravirpeste des petits ruminants virusruminantssignal pathway

Identifiers

PMID34552976

DOI10.3389/fvets.2021.722840

PMCPMC8450531

OpenAlexW3198423379

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.