Evidence map›Paper›PMID 34552875›Full record

ArticleFrontiers in oncology2021

Downregulation of GNA15 Inhibits Cell Proliferation

Mengya Li, Yu Liu, Yajun Liu, Lu Yang, Yan Xu, Weiqiong Wang, Zhongxing Jiang, Yanfang Liu, Shujuan Wang, Chong Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Mengya LiDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yu LiuDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yajun LiuDepartment of Orthopaedics, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI, United States.
Lu YangDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yan XuDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Weiqiong WangDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhongxing JiangDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanfang LiuDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shujuan WangDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Chong WangDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CNRhode Island Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognosis of acute myeloid leukemia (AML) with a normal karyotype is highly heterogonous, and the current risk stratification is still insufficient to differentiate patients from high-risk to standard-risk. Changes in some genetic profiles may contribute to the poor prognosis of AML. Although the prognostic value of G protein subunit alpha 15 (

methodsReverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to detect the mRNA expression level of

resultsThe expression of

conclusionsIn summary,

Indexed as

acute myeloid leukemiacell proliferationGNA15P38 MAPKprognosis

Identifiers

PMID34552875
PMCPMC8451478
OpenAlexW3197911423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.